7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7
- CAS No.
- 349553-94-2
- Chemical Name:
- 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7
- Synonyms
- Cholesterol Impurity 37;cholest-5-en-3,7α-diol-d7;7α-hydroxy Cholesterol-d7;cholest-5-en-3β,7α-diol-d7;cholest-5-en-3?,7α-diol-d7;7alpha-hydroxycholesterol-d7;7α-Hydroxycholesterol-25?26?26?26?27?27?27-[d7];7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7;CHOLEST-5-EN-3,7Α-DIOL-D7;7Α-HYDROXYCHOLESTEROL-D7
- CBNumber:
- CB3457203
- Molecular Formula:
- C26H37D7O2
- Molecular Weight:
- 395.67
- MDL Number:
- MFCD01317395
- MOL File:
- 349553-94-2.mol
7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25547 | 7α-hydroxy Cholesterol-d7 ≥99% deuterated forms (d1-d7) | 349553-94-2 | 1mg | $638 | 2024-03-01 | Buy |
| TRC | H917962 | 7α-Hydroxycholesterol-d7 | 349553-94-2 | 1mg | $495 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BAR0001509 | 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 95.00% | 349553-94-2 | 5MG | $500.23 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | D642 | 7α-Hydroxycholesterol-25,26,26,26,27,27,27-d7 97% | 349553-94-2 | 5mg | $1190 | 2021-12-16 | Buy |
7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 Chemical Properties,Uses,Production
Description
7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS. 7α-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholic acid (CA; ) and chenodeoxycholic acid (CDCA; ). It is formed via the oxidation of cholesterol by cholesterol 7α-hydroxylase/CYP7A1 in rat liver microsomes. 7α-hydroxy Cholesterol (40 μM) increases levels of the adhesion molecules ICAM-1, VCAM-1, and E-selectin in human umbilical vein endothelial cells (HUVECs). It increases secretion of chemokine (C-C motif) ligand 2 (CCL2) and matrix metalloproteinase-9 (MMP-9) in serum-deprived THP-1 cells when used at a concentration of 5 μg/ml. 7α-hydroxy Cholesterol has been found in macrophages isolated from atherosclerotic lesions in rabbits fed a high-cholesterol diet.
Uses
7α-hydroxycholesterol-d7 has been used as an internal standard for cholesterol and oxysterol measurement by gas chromatography-mass spectrometry (GC/MS).
General Description
7α-hydroxycholesterol is an oxysterol synthesized by the oxidation of the side chain of cholesterol. It is the precursor of bile acid.
7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 Preparation Products And Raw materials
Raw materials
Preparation Products
7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
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| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
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| Shanghai Jizhi Biochemical Technology Co. Ltd. | 400-400-400-9004166 18117592386 | 3007522982@qq.com | China | 52712 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
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| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | sinostandards@163.com | China | 5042 | 58 |