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FMOC-LYS(BOC)(ME)-OH

FMOC-LYS(BOC)(ME)-OH structure

CAS No.: 951695-85-5

Chemical Name:: FMOC-LYS(BOC)(ME)-OH

Synonyms: Fmoc-Lys(Me,Boc);FMOC-LYS(ME,BOC)-OH;FMOC-LYS(BOC)(ME)-OH;FMOC-L-LYS(BOC, ME)-OH;Boc-L-Lys(Fmoc)(Me)-OH;FMOC-LYSINE(BOC)(ME)-OH;Fmoc-Lys(Me,Boc)-OH,95%;Fmoc-Lys(Me,Boc)-OH, >=97%;FMOC-LYS(BOC)(ME)-OH USP/EP/BP;Fmoc-Lys(Me,Boc)-OH Novabiochem

CBNumber:: CB3465262

Molecular Formula:: C27H34N2O6

Molecular Weight:: 482.57

MDL Number:: MFCD01861332

MOL File:: 951695-85-5.mol

Last updated:2024-04-18 09:06:55

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FMOC-LYS(BOC)(ME)-OH Properties

Melting point	85-87℃
Boiling point	665.4±55.0 °C(Predicted)
Density	1.200
storage temp.	-20°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	3.88±0.21(Predicted)
InChIKey	JHMSFOFHTAYQLS-QHCPKHFHSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P271-P280
Hazard Codes	Xi
WGK Germany	WGK 2 water endangering
HS Code	2924 29 70

FMOC-LYS(BOC)(ME)-OH price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.52106	Fmoc-Lys(Me,Boc)-OH Novabiochem?	951695-85-5	500mg	$1000	2024-03-01	Buy
Sigma-Aldrich	8.52106	Fmoc-Lys(Me,Boc)-OH Novabiochem?	951695-85-5	1g	$1900	2024-03-01	Buy
TRC	F860973	Fmoc-lys(me,boc)-oh	951695-85-5	100mg	$660	2021-12-16	Buy
Apolloscientific	OR2236	N6-Methyl-L-lysine,N6-BOC,N2-FMOCprotected	951695-85-5	1g	$717	2021-12-16	Buy
Iris Biotech GmbH	FAA1448	Fmoc-L-Lys(Boc,Me)-OH	951695-85-5	1g	$756	2021-12-16	Buy

Product number	Packaging	Price	Buy
8.52106	500mg	$1000	Buy
8.52106	1g	$1900	Buy
F860973	100mg	$660	Buy
OR2236	1g	$717	Buy
FAA1448	1g	$756	Buy

FMOC-LYS(BOC)(ME)-OH Chemical Properties,Uses,Production

Description

Fmoc-lys (BOC) (ME)-OH is a kind of protected form of lysine. Lysine is double-protected by butyloxycarbonyl (BOC) and 9H-fluoren-9-ylmethoxycarbon (FMOC). It is a derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. The Boc protecting group can be removed through the TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.

Uses

Heterochromatin protein 1 (HP1) depends on trimethylation of H3 Lys 9; aggregation of chromatines depends on Lys methylation
Fmoc-Lys(Boc, Me)-OH is useful for preparing monomethylated histone fragments utilized in studying the regulatory roles of methylated histones. Fmoc-Lys(Boc,Me)-OH can be coupled using standard activating procedures. The Boc group on the side epsilon nitrogen atom is removed with TFA, usually at the same time as the peptide is cleaved from the resin.
Fmoc-Lys(Boc, Me)-OH is a novel derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting group occurs during the course of the TFA-mediated cleavage reaction.

General Description

Fmoc protected N-methylated lysine

References

http://www.chempep.com/ChemPep_Products2_Fmoc-Amino-Acid_Fmoc-Lys_Boc_Me_-OH.htm
https://en.wikipedia.org/wiki/Peptide_synthesis
Tung, C. L., et al. "A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation. " Chemical Communications 50.40(2014):5298-300.

FMOC-LYS(BOC)(ME)-OH synthesis

Synthesis of FMOC-LYS(BOC)(ME)-OH from Di-tert-butyl dicarbonate and Benzenebutanamide, N-8-quinolinyl-

FMOC-LYS(BOC)(ME)-OH Preparation Products And Raw materials

Raw materials

Benzenebutanamide, N-8-quinolinyl- Di-tert-butyl dicarbonate

Preparation Products

FMOC-LYS(BOC)(ME)-OH Suppliers

Global( 130)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alpha Biopharmaceuticals Co., Ltd	+86-411-39042497 +8613921981412	sales@alphabiopharm.com	China	886	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chengdu Feibo Pharm Technology Co., Ltd	15982321820	abby@arkpharm.com	CHINA	3279	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81148696 +8615536356810	1047@dideu.com	China	3408	58

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Biochempartner	58
Hubei xin bonus chemical co. LTD	58
Chengdu Feibo Pharm Technology Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58

Fmoc-Lys(Boc)(Me)-OH: Applications in Synthesis of Histone Tail Peptides and its Concise Preparation Method
Fmoc-Lys(Boc)(Me)-OH streamlines peptide synthesis, enabling precise integration and facilitating studies on histone modificat....
Apr 18，2024

FMOC-LYS(BOC)(ME)-OH: Synthesis and Application
FMOC-LYS(BOC)(ME)-OH is used as a pharmaceutical intermediate.
Dec 12，2022

View Lastest Price from FMOC-LYS(BOC)(ME)-OH manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-07-02	FMOC-LYS(BOC)(ME)-OH 951695-85-5	US $2250.00 / KG	1KG	98.0%	1T	Shaanxi Dideu Medichem Co. Ltd
	2019-07-06	FMOC-LYS(BOC)(ME)-OH 951695-85-5	US $1.00 / KG	1KG	99%	20kg	Career Henan Chemical Co

FMOC-LYS(BOC)(ME)-OH
951695-85-5
US $2250.00 / KG
98.0%
Shaanxi Dideu Medichem Co. Ltd

FMOC-LYS(BOC)(ME)-OH
951695-85-5
US $1.00 / KG
99%
Career Henan Chemical Co

FMOC-LYS(BOC)(ME)-OH Spectrum

FMOC-LYS(BOC)(ME)-OH(951695-85-5)FT-IR

951695-85-5(FMOC-LYS(BOC)(ME)-OH)Related Search:

(s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide FMoc-Aea-OH N(ALPHA)-FMOC-N(EPSILON)-DABCYL-L-LYSINE FMOC-LYS(DNP)-OH Fmoc-Lys(Trt)-OH

FMOC-D-LYS(IVDDE)-OH FMOC-LYS(ME)2-OH HCL FMOC-LYS(ME3)-OH HCL Fmoc-L-beta-Homoarginine(Pmc) Fmoc-N'-Acetyl-L-lysine

Fmoc-Lys(Pal-Glu-OtBu)-OH Fmoc-Lys(N3)-OH FMOC-LYS(FMOC)-OH Fmoc-L-Lys(Dde)-OH Fmoc-Lys(Ddiv)-OH

FMOC-LYS(BOC)(ISOPROPYL)-OH FMOC-LYS(BOC-ABZ)-OH FMOC-LYS(BOC)-LEU-OH

1of4

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-TERT-BUTYLOXYCARBONYL-N-EPSILON-METHYL-L-LYSINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-T-BUTYL-OXYCARBONYL-N-EPSILON-METHYL-L-LYSINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-T-BUTOXYCARBONYL-N-EPSILON-METHYL-L-LYSINE N-ALPHA-FMOC-N-EPSILON,EPSILON-T-BOC-METHYL-L-LYSINE N-ALPHA-FMOC-N-EPSILON-METHYL-N-EPSILON-T-BOC-L-LYSINE FMOC-LYS(BOC)(ME)-OH FMOC-LYSINE(BOC)(ME)-OH FMOC-L-LYS(BOC, ME)-OH N'-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N'-methyl-L-lysine (S)-1-(9H-fluoren-9-yl)-10,13,13-trimethyl-3,11-dioxo-2,12-dioxa-4,10-diazatetradecane-5-carboxylic acid FMoc-N-epsilon-Methyl-N-epsilon-t-Boc-L-lysine Fmoc-Lys(Me,Boc)-OH, >=97% Nalpha-Fmoc-Nepsilon-methyl-Nepsilon-Boc-L-lysine Fmoc-Lys(Me,Boc)-OH Novabiochem (9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(Boc, Me)-OH Fmoc-Lys(Me,Boc)-OH N-Fmoc-N'-Boc-N'-Methyl-Lysine N6-[(tert-Butoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-methyl-L-Lysine, 97% L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-methyl- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoicaci FMOC-LYS(BOC)(ME)-OH USP/EP/BP Boc-L-Lys(Fmoc)(Me)-OH N'-tert-butyloxycarbonyl-N-fluorenylmethoxycarbonyl-N'-methyl-L-lysine (2S)-6-{[(tert-butoxy)carbonyl](methyl)amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoic acid FMOC-LYS(ME,BOC)-OH Fmoc-Lys(Me,Boc) N6-Boc-N2-Fmoc-N6-methyl-L-lysine N2-(((9H-fluorene-9-yl)methoxy)oxo)-N6-(tertbutyloxyoxo)-N6-methyl-L-lysine Fmoc-Lys(Me,Boc)-OH,95% 951695-85-5 amino acids