ChemicalBook >> CAS DataBase List >>Delgocitinib
Delgocitinib
- CAS No.
- 1263774-59-9
- Chemical Name:
- Delgocitinib
- Synonyms
- JTE052;JTE-052;LEO124249;LEO 124249;Delgocitinib;Delgocitinib(JTE-052);Corectim(Delgocitinib);Delgocitinib (LEO124249;JTE052,Inhibitor,Janus kinase,inhibit,JAK,Delgocitinib,JTE 052;1,6-Diazaspiro[3.4]octane-1-propanenitrile, 3-methyl-β-oxo-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (3S,4R)-
- CBNumber:
- CB34667815
- Molecular Formula:
- C16H18N6O
- Molecular Weight:
- 310.35
- MDL Number:
- MFCD31630732
- MOL File:
- 1263774-59-9.mol
Last updated:2023-12-26 15:06:58
Density | 1.41±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Store at -20°C |
solubility | DMSO:58.0(Max Conc. mg/mL);186.89(Max Conc. mM) |
pka | -0.65±0.40(Predicted) |
FDA UNII | 9L0Q8KK220 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Delgocitinib price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-0031558 | Delgocitinib 99.76% | 1263774-59-9 | 10mg | $1100 | 2021-12-16 | Buy |
ChemScene | CS-0031558 | Delgocitinib 99.76% | 1263774-59-9 | 25mg | $2200 | 2021-12-16 | Buy |
ChemScene | CS-0031558 | Delgocitinib 99.76% | 1263774-59-9 | 50mg | $3500 | 2021-12-16 | Buy |
ChemScene | CS-0031558 | Delgocitinib 99.76% | 1263774-59-9 | 100mg | $5500 | 2021-12-16 | Buy |
ChemScene | CS-0031558 | Delgocitinib 99.76% | 1263774-59-9 | 1mg | $210 | 2021-12-16 | Buy |
Delgocitinib Chemical Properties,Uses,Production
Definition
ChEBI: Delgocitinib is a pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a (3S,4R)-1-(cyanoacetyl)-3-methyl-1,6-diazaspiro[3.4]octan-6-yl group at position 4. It is a pan-Janus kinase (JAK) inhibitor and is approved for treatment of atopic dermatitis (AD) in Japan. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor, an anti-inflammatory drug, an antipsoriatic and an antiseborrheic. It is a pyrrolopyrimidine, a tertiary amino compound, a nitrile, an azaspiro compound, a tertiary carboxamide and a N-acylazetidine.
Delgocitinib Preparation Products And Raw materials
Raw materials
Preparation Products
Delgocitinib Suppliers
Global( 43)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12550 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Nanjing Vcare PharmaTech Co., Ltd | 025-58741518 17366379912 | sales@vcarepharmatech.com | China | 462 | 58 |
Nanjing Tianhai Pharmaceutical Technology Co., Ltd. | 025-58351158 13851454004 | 3494688757@qq.com | China | 116 | 58 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4121 | 55 | |
Bayee Biotech (Anqing) Co., Ltd. | 0556-5032306 18917961636 | wtx@bayeebio.com | China | 303 | 61 |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 905 | 64 |
Related articles
- Synthesis of Delgocitinib
- Delgocitinib is synthesised using bromolactone as raw material by chemical reaction.
- Dec 26,2023
Delgocitinib
JTE052
JTE-052
LEO 124249
LEO124249
3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)- 1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile
1,6-Diazaspiro[3.4]octane-1-propanenitrile, 3-methyl-β-oxo-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (3S,4R)-
Corectim(Delgocitinib)
Delgocitinib(JTE-052)
Delgocitinib (LEO124249
3-[(3S,4R)-3-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile
JTE052,Inhibitor,Janus kinase,inhibit,JAK,Delgocitinib,JTE 052
1263774-59-9
263774-59-9