Pyruvate Kinase (PK)
- CAS No.
- Chemical Name:
- Pyruvate Kinase (PK)
- Synonyms
- Pyruvate Kinase (PK)
- CBNumber:
- CB34670561
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Pyruvate Kinase (PK) price More Price(3)
Pyruvate Kinase (PK) Chemical Properties,Uses,Production
Uses
Pyruvate Kinase (PK) has been used in the kinase assay.
Uses
Pyruvate kinase has been used to measure ATPase activity and in the determination of adenylate concentration.
General Description
ATP:pyruvate 2-O-phosphotransferase
Pyruvate kinase has a molar mass of 237,000 and exists as a tetramer. Each polypeptide chain of this tetramer has a molar mass of 57,200. The enzyme contains two identical catalytic particles called protomers. Each of these protomers contains two polypeptide chains. Each protomer contains one site each for Mn2+ and phosphoenolpyruvate.
Biochem/physiol Actions
Pyruvate kinase catalyzes the irreversible conversion of P-enolpyruvate and ADP to pyruvate and ATP with the utilization of a proton. The first step is the transfer of phosphate group from P-enolpyruvate to ADP with the formation of bound enolate of pyruvate and ATP. In the second step, a proton is added to enolate to generate the keto form of pyruvate. Apart from this, the enzyme exhibits other activities, such as ATP- and bicarbonate-dependent ATPase, phosphorylation of fluoride and hydroxylamine, ATP-dependent phosphorylation of glycolate, and decarboxylation of oxaloacetate.
Pyruvate Kinase (PK) Preparation Products And Raw materials
Raw materials
Preparation Products
Pyruvate Kinase (PK) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |