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TAPI-0

TAPI-0 Structure
TAPI-0 structure
CAS No.
163958-73-4
Chemical Name:
TAPI-0
Synonyms
TAPI;TAPI-0 >=95% (HPLC);N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-
CBNumber:
CB34670622
Molecular Formula:
C24H32N4O5
Molecular Weight:
456.53
MDL Number:
MOL File:
163958-73-4.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
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TAPI-0 Properties

Density 1.227±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO
form powder
pka 9.17±0.20(Predicted)
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310+P330
RIDADR  UN 2811 6.1 / PGIII

TAPI-0 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1292 TAPI-0 ≥95% (HPLC) 163958-73-4 1MG $351 2023-06-20 Buy
TRC T731300 TAPI0 163958-73-4 1mg $270 2021-12-16 Buy
Product number Packaging Price Buy
SML1292 1MG $351 Buy
T731300 1mg $270 Buy

TAPI-0 Chemical Properties,Uses,Production

Uses

TAPI 0 is a metalloprotease inhibitor, which inhibits the obligate intracellular human pathogen Chalmydia trachomitis.

Biochem/physiol Actions

TAPI-0 is a metalloproteinase inhibitor with selectivity for TACE (TNF-α converting enzyme/ADAM17; IC50 = 100 nM). TAPI-0 also inhibits of collagenase and gelatinase. Although not specific for TACE, TAPI-0 is extensively used to block TACE-mediated TNF-α shedding.

storage

Store at -20°C

TAPI-0 Preparation Products And Raw materials

Raw materials

Preparation Products

TAPI-0 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 eric@peptidego.com China 6119 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
BOC Sciences -- info@bocsci.com USA 0 65
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 17306812703 3007955328@qq.com China 5720 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2488 58
Supplier Advantage
Aladdin Scientific 		58
Sigma-Aldrich 80
Hangzhou Peptidego Biotech Co.,Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 65
Energy Chemical 58
Changzhou Furuisi Biotechnology Co., Ltd 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 58
Shanghai Tachizaki Biomedical Research Center 58
TAPI TAPI-0 >=95% (HPLC) L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl- N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide 163958-73-4