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5-NITRO-2-FUROYL CHLORIDE

CAS No.
25084-14-4
Chemical Name:
5-NITRO-2-FUROYL CHLORIDE
Synonyms
Ai3-23633;Einecs 246-607-6;5-nitrofuroyl chloride;5-NITRO-2-FUROYL CHLORIDE;2-Furoyl chloride, 5-nitro-;5-Nitro-2-furancarbonyl chloride;5-NITROFURAN-2-CARBONYL CHLORIDE;2-Furancarbonyl chloride, 5-nitro-;5-nitrofuran-2-carboxylic chloride;N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide
CBNumber:
CB3470912
Molecular Formula:
C5H2ClNO4
Molecular Weight:
175.53
MDL Number:
MFCD00039564
MOL File:
25084-14-4.mol
MSDS File:
SDS
Last updated:2022-12-30 16:20:48

5-NITRO-2-FUROYL CHLORIDE Properties

Melting point 34-41 °C
Boiling point 137-140°C 15mm
Density 1.588±0.06 g/cm3(Predicted)
Flash point 137-140°C/15mm
Sensitive Moisture Sensitive
BRN 139693
CAS DataBase Reference 25084-14-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  3261
WGK Germany  3
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  2932190090
NFPA 704
1
3 0

5-NITRO-2-FUROYL CHLORIDE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 683752 5-Nitro-2-furoyl chloride 95% 25084-14-4 5g $224 2024-03-01 Buy
Sigma-Aldrich 683752 5-Nitro-2-furoyl chloride 95% 25084-14-4 25g $908 2023-06-20 Buy
TRC N493865 5-Nitro-2-furoyl chloride 25084-14-4 5g $330 2021-12-16 Buy
TRC N493865 5-Nitro-2-furoyl chloride 25084-14-4 2.5g $240 2021-12-16 Buy
SynQuest Laboratories 4H54-5-Z8 5-Nitrofuran-2-carbonyl chloride 25084-14-4 5G $226 2021-12-16 Buy
Product number Packaging Price Buy
683752 5g $224 Buy
683752 25g $908 Buy
N493865 5g $330 Buy
N493865 2.5g $240 Buy
4H54-5-Z8 5G $226 Buy

5-NITRO-2-FUROYL CHLORIDE Chemical Properties,Uses,Production

Description

5-Nitrofuroyl chloride is a furan chain bound to an acyl and a nitro group. Nitrofuran derivatives have been used as antibiotic and antimicrobial drugs but the acyl group bound to furan (furoyl chloride) is an intermediate for the synthesis of pharmaceuticals (e.g. antibiotics). 5-Nitrofuroyl chloride has been used as a reagent for the synthesis of some compounds with antibacterial properties and other chemicals.

Uses

5-Nitrofuroyl chloride has been used in the synthesis of certain ureides of furanmonocarboxylic acid and in the synthesis of two salts of the mesoionic compound with an influence on the effectiveness of norfloxacin, tetracycline, and erythromycin. There is a study on the antibacterial effects of some 5-nirtofuroyl derivatives but not on 5-nitrofuroyl chloride. There are no reports on its commercial use.

Uses

5-Nitro-2-furoyl Chloride is used as reactant in the synthesis of several therapeutic agents.

Environmental Fate

5-Nitrofuroyl chloride is a colorless crystal with molecular weight of 175.53 g mol-1. It is stable under normal temperature and pressure on the basis of its melting point (38–14℃). There are no available data on its solubility in water. The bioaccumulation factor (BCF) for this compound is 4.29 at pH 7.4, which indicates low accumulation in aquatic organisms. The soil adsorption coefficient normalized to the content of organic carbon (Koc value) is 98.92 at pH 7.4, which indicates high mobility in soil.

645-12-5
25084-14-4
Synthesis of 5-NITRO-2-FUROYL CHLORIDE from 5-Nitro-2-furoic acid

5-NITRO-2-FUROYL CHLORIDE Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12382 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32360 55
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006608290; 18621169109 market03@meryer.com China 40241 62
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30132 84
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696; info@hanhongsci.com China 42982 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18739 57
5-NITROFURAN-2-CARBONYL CHLORIDE 5-NITRO-2-FUROYL CHLORIDE 2-Furancarbonyl chloride, 5-nitro- 2-Furoyl chloride, 5-nitro- 5-nitrofuroyl chloride Ai3-23633 Einecs 246-607-6 5-Nitro-2-furancarbonyl chloride 5-Nitro-2-furoyl chloride, predominantly trans, 97% 5-nitrofuran-2-carboxylic chloride N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide 25084-14-4 C5H2ClNO4 ACID CHLORIDE Building Blocks C4 to C7 Chemical Synthesis Furans Heterocyclic Building Blocks