METOCLOPRAMIDE-D3
- CAS No.
- 1216522-89-2
- Chemical Name:
- METOCLOPRAMIDE-D3
- Synonyms
- METOCLOPRAMIDE-D3;[2H3]-Metoclopramide;4-AMino-5-chloro-N-[2-(diethylaMino)ethyl]-2-(Methoxy-d3)benzaMide;4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(trideuteriomethoxy)benzamide;Metoclopramide D3Q: What is Metoclopramide D3 Q: What is the CAS Number of Metoclopramide D3 Q: What is the storage condition of Metoclopramide D3 Q: What are the applications of Metoclopramide D3
- CBNumber:
- CB3473786
- Molecular Formula:
- C14H19ClD3N3O2
- Molecular Weight:
- 302.81
- MDL Number:
- MFCD08063630
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
METOCLOPRAMIDE-D3 price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28885 | Metoclopramide-d3 | 1216522-89-2 | 500μg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 28885 | Metoclopramide-d3 | 1216522-89-2 | 1mg | $115 | 2024-03-01 | Buy |
| TRC | M338687 | Metoclopramide-d3 | 1216522-89-2 | 5mg | $185 | 2021-12-16 | Buy |
| AK Scientific | 9017CT | Metoclopramide-d3 | 1216522-89-2 | 1mg | $225 | 2021-12-16 | Buy |
METOCLOPRAMIDE-D3 Chemical Properties,Uses,Production
Description
Metoclopramide-d3 is intended for use as an internal standard for the quantification of metoclopramide by GC- or LC-MS. Metoclopramide is an orally bioavailable serotonin (5-HT) receptor 5-HT3 antagonist with Ki and IC50 values of 995 and 308 nM, respectively, in rat cortical membranes. It is also a dopamine D2 receptor antagonist (IC50 = 483 nM in rat brain synaptic membranes). Oral administration of metoclopramide inhibits emesis induced by cisplatin and apomorphine in ferrets and dogs with ED50 values of 6.17 and 0.45 mg/kg, respectively. Metoclopramide reversibly inhibits human acetylcholinesterase (AChE) isolated from the caudate nucleus (Kis = 9.3 and 82 μM for competitive and non-competitive inhibition, respectively). Formulations containing metoclopramide have been used as anti-emetic and antipsychotic agents.
Chemical Properties
White Crystalline Solid
Uses
Labelled dopamine D2 receptor antagonist. A labelled substituted benzamide with neuroleptic activity. Antiemetic.
METOCLOPRAMIDE-D3 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Guangzhou Tosun Pharmaceutical Limited | +8618922120635 | sales@toref-standards.com | China | 1000 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6818 | 65 |
| Artis Biotech Co. Ltd. | 19138486554 18582380095 | sales@artisbio.com | China | 3066 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55591 | 58 |
| TOSUN PHARM | 13326451905 | 2881290884@qq.com | China | 7394 | 58 |