Anti-BRCA1 Antibody

CAS No.
Chemical Name:
Anti-BRCA1 Antibody
Synonyms
Anti-BRCA1 Antibody
CBNumber:
CB34815874
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Anti-BRCA1 Antibody price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 07-434 Anti-BRCA1 Antibody serum, Upstate? 07-434 $443 2024-03-01 Buy
Sigma-Aldrich 07-434 Anti-BRCA1 Antibody serum, clone, Upstate? 100μL $425 2023-01-07 Buy
TRC AN00937 Anti-BRCA1 Antibody 50g $185 2021-12-16 Buy
TRC AN00938 Anti-BRCA1 Antibody 50g $185 2021-12-16 Buy
Product number Packaging Price Buy
07-434 07-434 $443 Buy
07-434 100μL $425 Buy
AN00937 50g $185 Buy
AN00938 50g $185 Buy

Anti-BRCA1 Antibody Chemical Properties,Uses,Production

Uses

Detect BRCA1 with Anti-BRCA1 Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IHC, IP & WB. This BRCA1 antibody has been tested in human samples.

General Description

Two major susceptibility genes for breast cancer, BRCA1 and BRCA2, have been identified. Both genes are considered to be tumor-suppressor genes. Mutations within BRCA1 and BRCA2 are responsible for most familial breast cancer cases. Functional analyses of the BRCA1 and BRCA2 gene products have established their dual participation in transcription regulation and DNA damage repair. BRCA1 affects cell cycle regulation and loss of BRCA1 function due to decreased expression leads to cell cycle arrest, through p53 and p21 genes. In vivo, BRCA1 and BRCA2 are expressed at maximal levels in rapidly proliferating cells. This feature is consistent with in vitro observations that BRCA1 and BRCA2 are expressed in a cell cycle-dependent manner. During mammary gland development, the expression of BRCA1 and BRCA2 is induced in rapidly proliferating cellular compartments.

Anti-BRCA1 Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-BRCA1 Antibody Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-BRCA1 Antibody