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InSolution p38 MAP Kinase Inhibitor III - Calbiochem

InSolution p38 MAP Kinase Inhibitor III - Calbiochem Structure
InSolution p38 MAP Kinase Inhibitor III - Calbiochem structure
CAS No.
Chemical Name:
InSolution p38 MAP Kinase Inhibitor III - Calbiochem
Synonyms
InSolution p38 MAP Kinase Inhibitor III - Calbiochem
CBNumber:
CB34817373
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
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InSolution p38 MAP Kinase Inhibitor III - Calbiochem price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 506148 InSolution p38 MAP Kinase Inhibitor III - Calbiochem 1mg $209 2023-06-20 Buy
Product number Packaging Price Buy
506148 1mg $209 Buy

InSolution p38 MAP Kinase Inhibitor III - Calbiochem Chemical Properties,Uses,Production

General Description

A cell-permeable, potent, selective, and ATP-competitive inhibitor of p38 MAP kinase (IC50 = 380 nM for p38α). Shown to effectively suppress LPS-induced cytokine release in vitro (IC50 = 160 nM for TNF-α release and 39 nM for IL-1β release, human PBMC) and in vivo (ED50 = 1.33 mg/kg for TNF-α release in mice). Exhibits reduced inhibitory activity against cytochrome P450-2D6 compared to SB 203580 (Cat. No 559389) and is better suited for use in animal models.

Biochem/physiol Actions

Cell permeable: yes

InSolution p38 MAP Kinase Inhibitor III - Calbiochem Preparation Products And Raw materials

Raw materials

Preparation Products

InSolution p38 MAP Kinase Inhibitor III - Calbiochem Suppliers

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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
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Sigma-Aldrich 80
InSolution p38 MAP Kinase Inhibitor III - Calbiochem