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Goserelin EP Impurity L ((D-Leu7)-Goserelin)

CAS No.
1926163-38-3
Chemical Name:
Goserelin EP Impurity L ((D-Leu7)-Goserelin)
Synonyms
800009L;Goserelin EP Impurity L;Goserelin EP Impurity L TFA;GoserelinEPImpurityL-Goserelin);(D-Ser(tBu)?,D-Leu?,Azagly??)-LHRH;Goserelin -lmpurity L[7-D-Leucine]goserelin;Goserelin EP Impurity L ((D-Leu7)-Goserelin);Goserelin Impurity 12 (Goserelin EP Impurity L);GoserelinEPImpurityLDiacetate-GoserelinDiacetate);L-Proline, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-(1,1-dimethylethyl)-D-seryl-D-leucyl-L-arginyl-, 2-(aminocarbonyl)hydrazide
CBNumber:
CB34843804
Molecular Formula:
C59H84N18O14
Molecular Weight:
1269.41
MDL Number:
MOL File:
1926163-38-3.mol
Last updated:2025-06-18 16:39:25

Goserelin EP Impurity L ((D-Leu7)-Goserelin) Properties

Density 1.50±0.1 g/cm3(Predicted)
pka 9.82±0.15(Predicted)
Sequence {Pyr}-His-Trp-Ser-Tyr-{d-Ser(tBu)}-{d-Leu}-Arg-Pro-{Azagly}-NH2

Goserelin EP Impurity L ((D-Leu7)-Goserelin) Chemical Properties,Uses,Production

Uses

(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1].

References

[1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499

Goserelin EP Impurity L ((D-Leu7)-Goserelin) Preparation Products And Raw materials

Raw materials

Preparation Products

Goserelin EP Impurity L ((D-Leu7)-Goserelin) Suppliers

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Goserelin EP Impurity L ((D-Leu7)-Goserelin) Goserelin EP Impurity L Goserelin Impurity 12 (Goserelin EP Impurity L) GoserelinEPImpurityL-Goserelin) GoserelinEPImpurityLDiacetate-GoserelinDiacetate) L-Proline, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-(1,1-dimethylethyl)-D-seryl-D-leucyl-L-arginyl-, 2-(aminocarbonyl)hydrazide (D-Ser(tBu)?,D-Leu?,Azagly??)-LHRH 800009L Goserelin EP Impurity L TFA Goserelin -lmpurity L[7-D-Leucine]goserelin 1926163-38-3