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Isoxazole

Description References
Isoxazole
Isoxazole structure
CAS No.
288-14-2
Chemical Name:
Isoxazole
Synonyms
ISOXAZOLE;Isooxazole;1,2-Oxazole;Isoxazole,99%;Isoxazole 99%;ISOXAZOLE 98+%;Isoxazole, 98.5%;Different oxazole;1-Oxa-2-azacyclopentadiene
CBNumber:
CB3485864
Molecular Formula:
C3H3NO
Formula Weight:
69.06
MOL File:
288-14-2.mol

Isoxazole Properties

Melting point:
-67.1°C
Boiling point:
93-95 °C(lit.)
Density 
1.078 g/mL at 25 °C(lit.)
vapor density 
2.4 (vs air)
refractive index 
n20/D 1.427(lit.)
Flash point:
48 °F
storage temp. 
Store at RT.
solubility 
167g/l
pka
-2.0(at 25℃)
BRN 
103773
InChIKey
CTAPFRYPJLPFDF-UHFFFAOYSA-N
CAS DataBase Reference
288-14-2(CAS DataBase Reference)
NIST Chemistry Reference
Isoxazole(288-14-2)
EPA Substance Registry System
Isoxazole(288-14-2)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02
Signal word  Danger
Hazard statements  H225
Precautionary statements  P210-P240-P241-P280a-P303+P361+P353-P501a
Hazard Codes  F,Xi
Risk Statements  11
Safety Statements  16-23/33-33-29-7/9
RIDADR  UN 1993 3/PG 2
WGK Germany  3
10
Hazard Note  Highly Flammable
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29349990

Isoxazole price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 151637 Isoxazole 99% 288-14-2 5g $25.1 2018-11-13 Buy
Sigma-Aldrich 151637 Isoxazole 99% 288-14-2 25g $107 2018-11-13 Buy
TCI Chemical I0372 Isoxazole >95.0%(GC) 288-14-2 5g $71 2018-11-22 Buy
Alfa Aesar L01607 Isoxazole, 99% 288-14-2 5g $22 2018-11-13 Buy

Isoxazole Chemical Properties,Uses,Production

Description

As an important class of heterocycles, isoxazole is a five membered heterocyclic compound with various pharmacological actions, which is found in some natural products, such as ibotenic acid. It is used in the formation of the basis for a number of drugs, such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.
The isoxazole ring is an essential pharmacophore in modern drug discovery. Some beta-lactamase-resistant antibiotics contain an isoxazole group, including cloxacillin, dicloxacillin, flucloxacillin, and the isoxazole group is also found in some steroid drug such as danazol.

References

https://en.wikipedia.org/wiki/Isoxazole
http://www.ijpcbs.com/files/volume3-2-2013/15.pdf

Chemical Properties

Colorless liquid

Uses

Natural insecticide.

Definition

ChEBI: A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.

Hazard

Narcotic and psychomimetic effects.

Isoxazole Preparation Products And Raw materials

Raw materials

Preparation Products


Isoxazole Suppliers

Global( 158)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63729 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40269 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15881 69
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30163 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24555 81
Beijing dtftchem Technology Co., Ltd. 13651141086; 86(10)60275028、60275820
86 (10) 60270825 dtftchem@sina.com China 3393 62

View Lastest Price from Isoxazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-24 Isoxazole
288-14-2
US $1.00 / KG 1KG 98% 100KG career henan chemical co

Isoxazole Spectrum


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