ChemicalBook >> CAS DataBase List >>DMH-25
DMH-25
- CAS No.
- 1685280-21-0
- Chemical Name:
- DMH-25
- Synonyms
- DMH-25;DMH25,DMH 25;6,8-dibromo-2-(4-bromophenyl)-3-nitro-2H-chromene;2H-1-Benzopyran, 6,8-dibromo-2-(4-bromophenyl)-3-nitro-
- CBNumber:
- CB34919770
- Molecular Formula:
- C15H8Br3NO3
- Molecular Weight:
- 489.94
- MDL Number:
- MOL File:
- 1685280-21-0.mol
Last updated:2023-03-31 09:12:58
DMH-25 Chemical Properties,Uses,Production
Description
DMH25 is a novel covalent and potent mTOR inhibitor, which shows in vivo antitumor activity against triple-negative breast cancer cells. ation. DHM25 was shown to be a selective and covalent inhibitor of mTOR using biochemical and cellular analyses, modeling, and a large panel of kinase activity assays spanning the human kinome (243 kinases). In vivo, DHM25 was an efficient inhibitor of growth and metastasis of triple-negative breast cancer cells, paving the way for its clinical application in oncology. Constitutive activation of the PI3K/mTOR signaling pathway contributes to carcinogenesis and metastasis in most, if not all, breast cancers.
DMH-25 Preparation Products And Raw materials
Raw materials
Preparation Products
DMH-25 Suppliers
Global( 4)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 | info@rovathin.com.cn | China | 9454 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 56 |
Suzhou Rovathin Foreign Trade Co.,Ltd | 58 |
TargetMol Chemicals Inc. | 58 |
DMH-25
6,8-dibromo-2-(4-bromophenyl)-3-nitro-2H-chromene
DMH25,DMH 25
2H-1-Benzopyran, 6,8-dibromo-2-(4-bromophenyl)-3-nitro-
1685280-21-0