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POLYPHYLLIN D

POLYPHYLLIN D structure

CAS No.: 50773-41-6

Chemical Name:: POLYPHYLLIN D

Synonyms: Paris I;Saponin Pa;Polyphyllin;Polyphyllin C;Polyphyllin I;POLYPHYLLIN D;Polyphyllin A;Polyphillin D;Polyphyllin Ⅰ;GLYCO-DIOSGENIN

CBNumber:: CB3511798

Molecular Formula:: C44H70O16

Molecular Weight:: 855.02

MDL Number:: MFCD12407435

MOL File:: 50773-41-6.mol

Last updated:2023-12-05 20:29:54

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POLYPHYLLIN D Properties

Melting point	>245°C (dec.)
Density	1.40
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly)
pka	12?+-.0.70(Predicted)
form	Solid
color	White

SAFETY

Risk and Safety Statements

HS Code	29389090

POLYPHYLLIN D price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	29179	Polyphyllin I	50773-41-6	5mg	$121	2024-03-01	Buy
Cayman Chemical	29179	Polyphyllin I	50773-41-6	50mg	$722	2024-03-01	Buy
Cayman Chemical	29179	Polyphyllin I	50773-41-6	10mg	$183	2024-03-01	Buy
Cayman Chemical	29179	Polyphyllin I	50773-41-6	25mg	$423	2024-03-01	Buy
Usbiological	294500	Polyphyllin A	50773-41-6	1mg	$333	2021-12-16	Buy

Product number	Packaging	Price	Buy
29179	5mg	$121	Buy
29179	50mg	$722	Buy
29179	10mg	$183	Buy
29179	25mg	$423	Buy
294500	1mg	$333	Buy

POLYPHYLLIN D Chemical Properties,Uses,Production

Description

Polyphyllin I is a steroid saponin that has been found in P. polyphylla and has anticancer activity. It decreases proliferation of, and induces apoptosis in, MCF-7 and MDA-MB-231 cells (IC₅₀s = 5 and 2.5 μM, respectively). It disrupts the mitochondrial membrane potential, activates caspase-3, and increases protein levels of the caspase-3 substrate poly(ADP-ribose) polymerase (PARP) in HepG2 and drug-resistant R-HepG2 cells. Polyphyllin I (2.05 and 2.73 mg/kg for 10 days) reduces tumor growth in an MCF-7 mouse xenograft model.

Uses

Polyphylin II is a natural saponin extracted from the plant, Paris polyphylla, and displays antiproliferative activity in vivo. Used in the treatment of lung and cervical cancers.

POLYPHYLLIN D Preparation Products And Raw materials

Raw materials

Preparation Products

POLYPHYLLIN D Suppliers

Global( 169)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58

Supplier	Advantage
Shaanxi Haibo Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Shanghai Standard Technology Co., Ltd.	58

View Lastest Price from POLYPHYLLIN D manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-22	Chondroitin Saponin 50773-41-6	US $225.00-65.00 / Kg/Bag	1Kg/Bag	0.98	20 tons	Sinoway Industrial co., ltd.
2024-04-12	POLYPHYLLIN D 50773-41-6	US $0.00 / kg	1kg	99%	2000ton	Shaanxi Haibo Biotechnology Co., Ltd
2023-02-24	Polyphyllin I 50773-41-6	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.

Chondroitin Saponin
50773-41-6
US $225.00-65.00 / Kg/Bag
0.98
Sinoway Industrial co., ltd.

POLYPHYLLIN D
50773-41-6
US $0.00 / kg
99%
Shaanxi Haibo Biotechnology Co., Ltd

Polyphyllin I
50773-41-6
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

POLYPHYLLIN D Spectrum

POLYPHYLLIN D(50773-41-6)¹HNMR

50773-41-6(POLYPHYLLIN D)Related Search:

(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene Nystatin Mesaconitine PolyphyllinH Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv.

ANTI-GALECTIN-7 POLYPHYLLIN E (RG) (3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside poricoic acid A 3-methyl ester Resibufogenin

formosanin C Pennogenin3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside Chonglou Saponin VII 22,25-Epoxy-2,3,14,20-tetrahydroxycholest-7-en-6-one beta-Sitosterol

Bufotaline ALLEOSIDE A Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-

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POLYPHYLLIN D Polyphyllin Polyphyllin I Polyphyllin C Paris saponin Pa Polyphillin D Polyphyllin A Paridis saponin I Paris I Saponin Pa Chonglou Saponin I(Polyphyllin A) Polyphyllin Ⅰ I,Chonglousaponin Polyphyllin I(Chonglou Saponin I) Polyphyllin D / Diosgenyl 4-O-α-L-arabinofuranosyl-2-O-α-L-rhamnopyranosyl-β -D-glucopyranoside Polyphyllin I, 98%, from Paris polyphylla Smith var.chinensis GLYCO-DIOSGENIN β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→2)]- POLYPHYLLIN D USP/EP/BP Chondroitin Saponin 50773-41-6 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract