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Vitamin A

Vitamin A
Vitamin A structure
CAS No.
11103-57-4
Chemical Name:
Vitamin A
Synonyms
ROIDEX;Aquasol A;VITAMIN A 500W;Vitamin A Retinol;Vitamin A USP/EP/BP;New anti-aging products;Water-soluble vitamin A;3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraen-1-ol
CBNumber:
CB3512063
Molecular Formula:
C20H30O
Formula Weight:
286.46
MOL File:
11103-57-4.mol

Vitamin A Properties

storage temp. 
-20°C
solubility 
All retinol esters are practically insoluble in water, soluble or partly soluble in anhydrous ethanol and miscible with organic solvents. Vitamin A and its esters are very sensitive to the action of air, oxidising agents, acids, light and heat. Carry out the assay and all tests as rapidly as possible, avoiding exposure to actinic light and air, oxidising agents, oxidation catalysts (e.g. copper , iron), acids and heat; use freshly prepared solutions.
NCI Drug Dictionary
Aquasol A
EPA Substance Registry System
Vitamin A (11103-57-4)
SAFETY
  • Risk and Safety Statements
Hazard Codes  T
Risk Statements  61
Safety Statements  53-45

Vitamin A price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation VIT0000040 VITAMIN A 95.00% 11103-57-4 100MG $613.65 2021-12-16 Buy
American Custom Chemicals Corporation VIT0000040 VITAMIN A 95.00% 11103-57-4 250MG $667.98 2021-12-16 Buy

Vitamin A Chemical Properties,Uses,Production

Chemical Properties

Retinol acetate: pale-yellow crystals (mp: about 60 °C). Once melted retinol acetate tends to yield a supercooled melt. Retinol propionate: reddish-brown oily liquid. Retinol palmitate: a fat-like, light yellow solid or a yellow oily liquid, if melted (mp: about 26 °C).

History

The structure of vitamin A and some of the important derivatives are shown in Figure 1. The parent structure is all-trans-retinol [CAS: 68-26-8] and its IUPAC name is (all-E)-3,7-dimethyl-9-(2,6,6- trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol. The numbering system for vitamin A derivatives parallels the system used for the carotenoids. In older literature, vitamin A compounds are named as derivatives of trimethyl cyclohexene and the side chain is named as a substituent. For retinoic acid derivatives, the carboxyl group is denoted as C-1 and the trimethyl cyclohexane ring as a substituent on C-9. The structures of vitamin A and β-carotene were elucidated by Karrer in 1930 and several derivatives of the vitamin were prepared by this group. In 1935, Wald isolated a substance found in the visual pigments of the eye and was able to show that this material was identical with Karrer’s retinaldehyde.

Uses

vitamin A can act as a keratinization regulator, helping to improve the skin’s texture, firmness, and smoothness. Vitamin A esters, once in the skin, convert to retinoic acid and provide anti-aging benefits. Vitamin A is believed to be essential for the generation and function of skin cells. Continued vitamin A deficiency shows a degeneration of dermal tissue, and the skin becomes thick and dry. Surface application of vitamin A helps prevent skin dryness and scaliness, keeping the skin healthy, clear, and infection resistant. Its skin regeneration properties appear enhanced when combined with vitamin e. Vitamin A is a major constituent of such oils as cod liver and shark, and many fish and vegetable oils. See also retinol; retinoic acid; retinylpalmitate.

General Description

The provitamin A carotenoids are obtained from plant sources and comprise some of the best sources of this vitamin. The provitamin As are found in deep green, yellow,and orange fruits and vegetables, such as carrots, spinach, broccoli, kale, collard and turnip greens, mangoes, apricots, nectarines, pumpkins, and sweet potatoes.
Vitamin A belongs to a class of compounds referred to as the retinoids, which consist of four isoprenoid units joined in a head-to-tail manner. All double bonds in the isoprenoid units are implied to be in the E (trans) configuration unless stated otherwise. Currently, the term retinoid is applied to retinol and its naturally occurring derivatives plus synthetic analogs, which need not have vitamin A activity. Vitamin A is currently used as a generic descriptor for all retinoids that exhibit the biological activity of retinol, the original substance identified as vitamin A. The term vitamin A1 and all-trans retinol have been used to refer to retinol whereas vitamin A2 was used to refer to 3,4-dehydroretinol.

General Description

Yellow crystals or orange solid. Practically water insoluble.

Air & Water Reactions

Practically water insoluble.

Reactivity Profile

Vitamin A is light sensitive. Also air sensitive and heat sensitive. Reacts with strong oxidizing agents. Also can react with acids . Can react exothermically with reducing agents to release hydrogen gas.

Fire Hazard

Flash point data for Vitamin A are not available. Vitamin A is probably combustible.

Clinical Use

Vitamin A is used in the treatment of known or suspected vitamin A deficiency. Of course, vaccination is of prime importance; however, in underdeveloped countries where the rate of vaccination is low, vitamin A supplementation is a beneficial alternative.Retinoate analogs have been developed for use in the treatment of dermatological conditions such as psoriasis and acne.

Vitamin A Preparation Products And Raw materials

Raw materials

Preparation Products


Vitamin A Suppliers

Global( 103)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Chengdu GLP biotechnology Co Ltd
13350802083 028-87075086
scglp@glp-china.com CHINA 1824 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
career henan chemical co
15093356674 0371-55982848
0086-371-86658258 factory@coreychem.com CHINA 29863 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
86-021-61999440
contact@trustwe.com CHINA 10008 58
Hebei Mojin Biotechnology Co., Ltd
0086 15533627333
admin@hbmojin.com CHINA 1011 58
Hebei Yirun Sega Biological Technology Co. Ltd
19932103556 +8619932103556
+8619932103556 linda@yrsjbiotech.com CHINA 1691 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30014 58

View Lastest Price from Vitamin A manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-11-15 Vitamin A
11103-57-4
US $25.00 / KG 1KG 99% 5ton/Month Hebei Yirun Sega Biological Technology Co. Ltd
2021-07-30 Vitamin A USP/EP/BP
11103-57-4
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
2021-07-10 Vitamin A
11103-57-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

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