VP3.15 Dihydrobromide
- CAS No.
- 1281681-33-1
- Chemical Name:
- VP3.15 Dihydrobromide
- Synonyms
- VP3.15 Dihydrobromide;VP3.15 dihydrobromide, 10 mM in DMSO;N-(2-Morpholinoethyl)-2,3-diphenyl-1,2,4-thiadiazol-5(2H)-imine dihydrobromide;Glycogen synthase kinase-3,VP3.15 dihydrobromide,inhibit,Inhibitor,VP-3.15 dihydrobromide,Glycogen synthase kinase 3,GSK-3,Phosphodiesterase (PDE)
- CBNumber:
- CB35441036
- Molecular Formula:
- C20H23BrN4OS
- Molecular Weight:
- 447.4
- MDL Number:
- MOL File:
- 1281681-33-1.mol
VP3.15 Dihydrobromide price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-0101863 | VP3.15(dihydrobromide) 98.22% | 1281681-33-1 | 5mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-0101863 | VP3.15(dihydrobromide) 98.22% | 1281681-33-1 | 10mg | $250 | 2021-12-16 | Buy |
ChemScene | CS-0101863 | VP3.15(dihydrobromide) 98.22% | 1281681-33-1 | 50mg | $900 | 2021-12-16 | Buy |
ChemScene | CS-0101863 | VP3.15(dihydrobromide) 98.22% | 1281681-33-1 | 100mg | $1550 | 2021-12-16 | Buy |
DC Chemicals | 027577 | VP3.15dihydrobromide | 1281681-33-1 | 003 | $2200 | 2021-12-16 | Buy |
VP3.15 Dihydrobromide Chemical Properties,Uses,Production
Description
VP3.15 Dihydrobromide is a novel dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor.
Uses
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS)[1].
target
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
References
[1] Medina-Rodríguez EM, et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis. Sci Rep. 2017 Mar 3;7:43545. DOI:10.1038/srep43545
VP3.15 Dihydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
VP3.15 Dihydrobromide Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
Chembest Research Laboratories Limited | +86-21-20908456 | sales@BioChemBest.com | China | 6005 | 61 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7787 | 56 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4611 | 55 | |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
View Lastest Price from VP3.15 Dihydrobromide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-05-06 | VP3.15 dihydrobromide
1281681-33-1
|
US $64.00-228.00 / mg | 98% | 10g | TargetMol Chemicals Inc. |
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- VP3.15 dihydrobromide
1281681-33-1
- US $64.00-228.00 / mg
- 98%
- TargetMol Chemicals Inc.