ChemicalBook >> CAS DataBase List >>VP3.15 Dihydrobromide

VP3.15 Dihydrobromide

CAS No.
1281681-33-1
Chemical Name:
VP3.15 Dihydrobromide
Synonyms
VP3.15 Dihydrobromide;VP3.15 dihydrobromide, 10 mM in DMSO;N-(2-Morpholinoethyl)-2,3-diphenyl-1,2,4-thiadiazol-5(2H)-imine dihydrobromide;Glycogen synthase kinase-3,VP3.15 dihydrobromide,inhibit,Inhibitor,VP-3.15 dihydrobromide,Glycogen synthase kinase 3,GSK-3,Phosphodiesterase (PDE)
CBNumber:
CB35441036
Molecular Formula:
C20H23BrN4OS
Molecular Weight:
447.4
MDL Number:
MOL File:
1281681-33-1.mol
Last updated:2025-05-06 17:12:13

VP3.15 Dihydrobromide Properties

storage temp. Store at -20°C
solubility dmso:62.5(Max Conc. mg/mL);118.3(Max Conc. mM)
form Solid
color Light yellow to yellow

VP3.15 Dihydrobromide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0101863 VP3.15(dihydrobromide) 98.22% 1281681-33-1 5mg $150 2021-12-16 Buy
ChemScene CS-0101863 VP3.15(dihydrobromide) 98.22% 1281681-33-1 10mg $250 2021-12-16 Buy
ChemScene CS-0101863 VP3.15(dihydrobromide) 98.22% 1281681-33-1 50mg $900 2021-12-16 Buy
ChemScene CS-0101863 VP3.15(dihydrobromide) 98.22% 1281681-33-1 100mg $1550 2021-12-16 Buy
DC Chemicals 027577 VP3.15dihydrobromide 1281681-33-1 003 $2200 2021-12-16 Buy
Product number Packaging Price Buy
CS-0101863 5mg $150 Buy
CS-0101863 10mg $250 Buy
CS-0101863 50mg $900 Buy
CS-0101863 100mg $1550 Buy
027577 003 $2200 Buy

VP3.15 Dihydrobromide Chemical Properties,Uses,Production

Description

VP3.15 Dihydrobromide is a novel dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor.

Uses

VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS)[1].

target

VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.

References

[1] Medina-Rodríguez EM, et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis. Sci Rep. 2017 Mar 3;7:43545. DOI:10.1038/srep43545

VP3.15 Dihydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

VP3.15 Dihydrobromide Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38664 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6005 61
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7787 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4611 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60

View Lastest Price from VP3.15 Dihydrobromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VP3.15 dihydrobromide pictures 2025-05-06 VP3.15 dihydrobromide
1281681-33-1
US $64.00-228.00 / mg 98% 10g TargetMol Chemicals Inc.

VP3.15 Dihydrobromide Spectrum

VP3.15 Dihydrobromide Glycogen synthase kinase-3,VP3.15 dihydrobromide,inhibit,Inhibitor,VP-3.15 dihydrobromide,Glycogen synthase kinase 3,GSK-3,Phosphodiesterase (PDE) N-(2-Morpholinoethyl)-2,3-diphenyl-1,2,4-thiadiazol-5(2H)-imine dihydrobromide VP3.15 dihydrobromide, 10 mM in DMSO 1281681-33-1