ChemicalBook >> CAS DataBase List >>JAK-IN-3
JAK-IN-3
- CAS No.
- 1400876-94-9
- Chemical Name:
- JAK-IN-3
- Synonyms
- JAK-IN-3;JAKIN3,JAK IN 3;JAK-IN-3 (COMPOUND 22);Pyrrolo[1,2-b]pyridazine-3-carboxamide, 4-[[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]amino]-6-phenyl-
- CBNumber:
- CB35540371
- Molecular Formula:
- C18H20N4O3
- Molecular Weight:
- 340.38
- MDL Number:
- MFCD31813914
- MOL File:
- 1400876-94-9.mol
Last updated:2023-05-21 10:59:17
JAK-IN-3 Chemical Properties,Uses,Production
Biological Activity
JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].
References
[1]. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.
JAK-IN-3 Preparation Products And Raw materials
Raw materials
Preparation Products
JAK-IN-3 Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10011 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| cjbscvictory | 58 |
| TargetMol Chemicals Inc. | 58 |
JAK-IN-3 (COMPOUND 22)
JAK-IN-3
JAKIN3,JAK IN 3
Pyrrolo[1,2-b]pyridazine-3-carboxamide, 4-[[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]amino]-6-phenyl-
1400876-94-9