(D-Ala2)-Leu-Enkephalin
- CAS No.
- 64963-01-5
- Chemical Name:
- (D-Ala2)-Leu-Enkephalin
- Synonyms
- (D-ALA2)-LEU-ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;D-ALA2-LEU5-ENKEPHALIN;(D-Ala)-Leu-Enkephalin;Tyr-D-Ala-Gly-Phe-Leu-OH;Pentapeptide-3/Leuphasyl;H-TYR-D-ALA-GLY-PHE-LEU-OH;Leuphasyl / Pentapeptide-3;[D-ALA2]-LEUCINE ENKEPHALIN;Leuphasyl / Pentapeptide-18
- CBNumber:
- CB3667734
- Molecular Formula:
- C29H39N5O7
- Molecular Weight:
- 569.65
- MDL Number:
- MFCD00076409
- MOL File:
- 64963-01-5.mol
Melting point | 160-163.5 °C |
---|---|
Boiling point | 991.9±65.0 °C(Predicted) |
Density | 1.257±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | DMF (Slightly), DMSO (Slightly) |
form | Solid |
pka | 3.40±0.10(Predicted) |
color | White to Off-White |
InChIKey | ZHUJMSMQIPIPTF-JMBSJVKXSA-N |
SMILES | C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N |
FDA UNII | PO4D55T1IG |
(D-Ala2)-Leu-Enkephalin price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | E5008 | [D-Ala2]-Leucine enkephalin ≥97% (HPLC) | 64963-01-5 | 5mg | $98.9 | 2024-03-01 | Buy |
ChemScene | CS-5905 | [D-Ala2]-Leucine enkephalin 99.77% | 64963-01-5 | 10mg | $108 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA108766 | (D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH | 64963-01-5 | 25mg | $181 | 2021-12-16 | Buy |
ChemScene | CS-5905 | [D-Ala2]-Leucine enkephalin 99.77% | 64963-01-5 | 50mg | $420 | 2021-12-16 | Buy |
Activate Scientific | AS112962 | [D-Ala2]-Leucine enkephalin 97% | 64963-01-5 | 25mg | $424 | 2021-12-16 | Buy |
(D-Ala2)-Leu-Enkephalin Chemical Properties,Uses,Production
Definition
The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.
benefits
(D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions.
References
[1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644.
(D-Ala2)-Leu-Enkephalin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 999 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 | asdf@shanghaihg.cn | China | 265 | 58 |
Wuhan Cell Pharmaceutical Co., Ltd | +86-13129979210 +86-13129979210 | sales@cellwh.com | China | 376 | 58 |
Wuhan Haorong Biotechnology Co.,ltd | +86-18565342920; +8618565342920 | sales@chembj.net | China | 289 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 | admin@oudaxin.com | China | 114 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 973 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 1143 | 58 |
Shanghai Getian Industrial Co., LTD | +86-15373193816 +86-15373193816 | mike@ge-tian.com | China | 269 | 58 |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | sales@alabiochem.com | China | 888 | 58 |
View Lastest Price from (D-Ala2)-Leu-Enkephalin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-19 | TYR-D-ALA-GLY-PHE-LEU
64963-01-5
|
US $200.00-170.00 / KG | 1KG | 99% | 20 tons | Hong Kong Excellence Biotechnology Co., Ltd. | ||
2024-09-19 | Pentapeptide-18
64963-01-5
|
US $30.00 / kg | 1kg | 99% | 2000kg | hebei hongtan Biotechnology Co., Ltd | ||
2024-09-18 | Leuphasyl;Pentapeptide-18
64963-01-5
|
US $1.00 / kit | 1kit | 99% | 1000kit | Wuhan Cell Pharmaceutical Co., Ltd |
- TYR-D-ALA-GLY-PHE-LEU
64963-01-5
- US $200.00-170.00 / KG
- 99%
- Hong Kong Excellence Biotechnology Co., Ltd.
- Pentapeptide-18
64963-01-5
- US $30.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
- Leuphasyl;Pentapeptide-18
64963-01-5
- US $1.00 / kit
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
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