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BISNORCHOLENALDEHYDE

BISNORCHOLENALDEHYDE Structure
BISNORCHOLENALDEHYDE structure
CAS No.
3986-89-8
Chemical Name:
BISNORCHOLENALDEHYDE
Synonyms
BNKY018-PG01;Bisnorcholeldehyde;KETOBISNORALDEHYDE;Bisnorcholenaldehyde;Progesterone Impurity 7;Progesterone Impurity 24;Progesterone EP Impurity I;Didroprogesterone impurity 2;Progesterone EP Impurity I-02;(20S)-20-Formylpregn-4-en-3-one
CBNumber:
CB3670455
Molecular Formula:
C22H32O2
Molecular Weight:
328.49
MDL Number:
MFCD00056488
MOL File:
Mol file
MSDS File:
SDS
Last updated:2024-03-19 09:41:09
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BISNORCHOLENALDEHYDE Properties

Melting point 159-160 °C
Boiling point 459.4±14.0 °C(Predicted)
Density 1.07±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H351-H362-H360
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313

BISNORCHOLENALDEHYDE Chemical Properties,Uses,Production

Description

Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.

Uses

Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.

References

[1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.

BISNORCHOLENALDEHYDE synthesis

40736-33-2
3986-89-8
Synthesis of BISNORCHOLENALDEHYDE from 3-keto-23,24-bisnorchol-4-en-22-ol

BISNORCHOLENALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

21-hydroxy-20-methylpregn-4-en-3-one

BISNORCHOLENALDEHYDE Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
BIONNA MEDICINE CO.,LTD 		01056380788-8515; +8618518759099 790226113@qq.com China 52 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Shenzhen Excellent Biomedical Technology Co.,Ltd. 		+86-0755-26050679 +86-15915472436 sale@ex-biotech.cn China 1031 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
Shijiazhuang yaoBo Pharmaceutical Co., Ltd. 15633056635 2880679888@qq.com China 2684 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 7851 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55717 58
Supplier Advantage
BIONNA MEDICINE CO.,LTD 		58
Standardpharm Co. Ltd. 		58
Shenzhen Excellent Biomedical Technology Co.,Ltd. 		58
China National Standard Pharmaceutical Corporation Limited 		58
J & K SCIENTIFIC LTD. 76
ChemStrong Scientific Co.,Ltd 56
Shanghai Kewel Chemical Co., Ltd. 50
Shijiazhuang yaoBo Pharmaceutical Co., Ltd. 58
Hubei Yangxin Medical Technology Co., Ltd. 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58

BISNORCHOLENALDEHYDE Spectrum

BISNORCHOLENALDEHYDE(3986-89-8)MSBISNORCHOLENALDEHYDE(3986-89-8)1HNMRBISNORCHOLENALDEHYDE(3986-89-8)13CNMR

3986-89-8(BISNORCHOLENALDEHYDE)Related Search:

20α-Acetoxy-4-pregnen-3-one (17α)-Pregn-4-ene-3,20-dione 4-PREGNEN-20-ALPHA-OL-3-ONE 4,9(11)-PREGNADIEN-3,20-DIONE 4-PREGNEN-20-BETA-OL-3-ONE
1,4-PREGNADIEN-3,20-DIONE Progesterone EP Impurity G Progesterone EP Impurity F Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one
Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-
N-(1-Cyclohexen-1-yl)morpholine Abiraterone Pregna-4,6-diene-3,20-dione

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KETOBISNORALDEHYDE 3-KETO-4-PREGNENE-20-BETA-CARBOXALDEHYDE 4-PREGNEN-20BETA-CARBOXALDEHYDE-3-ONE 4-PREGNEN-3-ONE-20-BETA-CARBOXALDEHYDE Progesterone EP Impurity I Progesterone Impurity 7 Progesterone EP Impurity I (S-isomer) (20S)-3-oxopregn-4-ene-20-carboxaldehyde BNKY018-PG01 Bisnorcholeldehyde Pregn-4-ene-20-carboxaldehyde, 3-oxo-, (20S)- (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal 3-Oxo-pregn-4-ene-20α- carboxaldehyde Progesterone Impurity 24 (20S)-20-Formylpregn-4-en-3-one (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal (Progesterone Impurity) Didroprogesterone impurity 2 Progesterone EP Impurity I-02 Bisnorcholenaldehyde 3986-89-8