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4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER

CAS No.
65874-27-3
Chemical Name:
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
Synonyms
tert-butyl 4-forMylbenzoate;4-(tert-Butoxycarbonyl)benzaldehyde;4-Formylbenzoic Acid tert-Butyl Ester;4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER;Benzoic acid, 4-formyl-, 1,1-dimethylethyl ester;4-ForMyl-benzoic acid Mono tert-butyl ester(70%)
CBNumber:
CB3684128
Molecular Formula:
C12H14O3
Molecular Weight:
206.24
MDL Number:
MFCD01111994
MOL File:
65874-27-3.mol
Last updated:2025-07-24 18:13:53
Product description Number Pack Size Price
tert-Butyl 4-Formylbenzoate >98.0%(GC) B5414 1g $199
tert-Butyl 4-Formylbenzoate >98.0%(GC) B5414 5g $492
tert-Butyl 4-Formylbenzoate B745425 10mg $45
4-Formyl-benzoic acid mono tert-butyl ester >95% 102870 500mg $544
tert-Butyl 4-Formylbenzoate >98.0% CS-W007267 10g $299

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Properties

Melting point 52.0 to 56.0 °C
Boiling point 310.7±25.0 °C(Predicted)
Density 1.093±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
color White to Orange to Green

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2916399090

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B5414 tert-Butyl 4-Formylbenzoate >98.0%(GC) 65874-27-3 1g $199 2025-07-31 Buy
TCI Chemical B5414 tert-Butyl 4-Formylbenzoate >98.0%(GC) 65874-27-3 5g $492 2025-07-31 Buy
TRC B745425 tert-Butyl 4-Formylbenzoate 65874-27-3 10mg $45 2021-12-16 Buy
Matrix Scientific 102870 4-Formyl-benzoic acid mono tert-butyl ester >95% 65874-27-3 500mg $544 2021-12-16 Buy
ChemScene CS-W007267 tert-Butyl 4-Formylbenzoate >98.0% 65874-27-3 10g $299 2021-12-16 Buy
Product number Packaging Price Buy
B5414 1g $199 Buy
B5414 5g $492 Buy
B745425 10mg $45 Buy
102870 500mg $544 Buy
CS-W007267 10g $299 Buy

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Chemical Properties,Uses,Production

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

4-Formylbenzoic acid

619-66-9

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER

65874-27-3

Example 1 Synthesis of tert-butyl 4-formylbenzoate: To a 250 mL round bottom flask were sequentially added tert-butyl para-formylbenzoate (5.0 g, 33 mmol), di-tert-butyl dicarbonate (14.54 g, 66.6 mmol), 4-dimethylaminopyridine (0.814 g, 6.66 mmol) and tetrahydrofuran (100 mL). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give the crude product. Ethyl acetate (150 mL) was added to the residue and washed with saturated sodium bicarbonate solution (25 mL) and water (25 mL). After partitioning, the aqueous phase was back-extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, washed with saturated saline (50 mL), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. Finally, it was purified by fast column chromatography (eluent: petroleum ether to 10% ethyl acetate-petroleum ether gradient elution) to give tert-butyl 4-formylbenzoate (1.90 g, 28% yield) as a white solid. The product was characterized by 1H NMR (CDCl3, 400 MHz): δ 10.10 (s, 1H), 8.14 (d, J = 8.3 Hz, 2H), 7.93 (d, J = 8.5 Hz, 2H), 1.61 (s, 9H).

References

[1] Journal of the American Chemical Society,
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 7488 - 7489
[3] Patent: US2003/176495, 2003, A1
[4] Patent: US2011/212969, 2011, A1. Location in patent: Page/Page column 109

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Preparation Products And Raw materials

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Suppliers

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View Lastest Price from 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER pictures 2020-01-15 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
65874-27-3
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Spectrum

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER tert-butyl 4-forMylbenzoate 4-ForMyl-benzoic acid Mono tert-butyl ester(70%) Benzoic acid, 4-formyl-, 1,1-dimethylethyl ester 4-(tert-Butoxycarbonyl)benzaldehyde 4-Formylbenzoic Acid tert-Butyl Ester 65874-27-3