Chinese Japanese Germany Korea


Brand Name(s)
Amoxicillin structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

Amoxicillin Properties

storage temp. 
Do you have solubility information on this product that you would like to share
pKa 2.4 (Uncertain)
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
26787-78-0(CAS DataBase Reference)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi
Risk Statements  42/43
Safety Statements  22-36/37
WGK Germany  2
RTECS  XH8300000
HS Code  29411000
Hazardous Substances Data 26787-78-0(Hazardous Substances Data)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Amoxicillin price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A8523 Amoxicillin potency: ≥900μg per mg 26787-78-0 1g $37.6 2018-11-20 Buy
Sigma-Aldrich A8523 Amoxicillin potency: ≥900μg per mg 26787-78-0 5g $61.3 2018-11-20 Buy
Sigma-Aldrich A8523 Amoxicillin potency: ≥900μg per mg 26787-78-0 25g $209 2018-11-20 Buy

Amoxicillin Chemical Properties,Uses,Production

Brand Name(s)

Amoxicillin Amoxi-Tabs, Amoxi-Drops, Amoxi-Inject, Robamox-V, Biomox, and other brands; Amoxil, Trimox, Wymox, Polymox, (human forms); Amoxicillin trihydrate

Chemical Properties



Antibacterial;Bacterial transpeptidase inhibitor


ChEBI: A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group.

brand name

Amoxil (GlaxoSmithKline); Dispermox (Ranbaxy); Larotid (GlaxoSmithKline); Trimox (Apothecon) [Name previously used: Amoxycillin.].

Antimicrobial activity

The antibacterial spectrum is identical to that of ampicillin and there are few differences in antibacterial activity . Like ampicillin, amoxicillin is unstable to most β-lactamases. It has useful activity against Helicobacter pylori (<1% resistance), and is included in most combination regimens for the treatment of H. pylori infections.

Acquired resistance

There is complete cross-resistance with ampicillin. Its action against many β-lactamase-producing strains can be restored by co-administration with β-lactamase inhibitors.

Contact allergens

Amoxicillin is both a topical and a systemic sensitizer. Topical sensitization occurs in health care workers. Systemic drug reactions are frequent, such as urticaria, maculo-papular rashes, baboon syndrome, acute generalized exanthematous pustulosis, or even toxic epidermal necrosis. Cross-reactivity is common with ampicillin, and can occur with other penicillins.


Oral absorption: 75–90%
Cmax 500 mg oral: 5.5–7.6 mg/L after 1–2 h
500 mg intramuscular: c. 14 mg/L after 1–2 h
Plasma half-life: 1 h
Volume of distribution: 0.3 L/kg
Plasma protein binding: 17–20%
Absorption and distribution
Oral absorption produces over twice the peak concentration achieved by comparable doses of ampicillin, allowing less frequent dosing intervals. Absorption is unaffected by food. It is well-distributed in multiple body fluids, including pleural, peritoneal and middle ear fluid. It does not penetrate well into the CSF.
Metabolism and excretion
Some 10–25% is converted to the penicilloic acid. Between 50% and 70% of unchanged drug is recovered in the urine in the first 6 h after a dose of 250 mg. Plasma levels are elevated and prolonged by the administration of probenecid.

Clinical Use

Amoxicillin, 6-[D-(-)-α-amino-p- hydroxyphenylacetamido]penicillanic acid (Amoxil, Larotid, Polymox), a semisyntheticpenicillin introduced in 1974, is simply the p-hydroxyanalog of ampicillin, prepared by acylation of 6-APA with phydroxyphenylglycine.Its antibacterial spectrum is nearly identical with that ofampicillin, and like ampicillin, it is resistant to acid, susceptibleto alkaline and β-lactamase hydrolysis, andweakly protein bound. Early clinical reports indicated thatorally administered amoxicillin possesses significantadvantages over ampicillin, including more complete GIabsorption to give higher plasma and urine levels, lessdiarrhea, and little or no effect of food on absorption.50Thus, amoxicillin has largely replaced ampicillin for thetreatment of certain systemic and urinary tract infectionsfor which oral administration is desirable. Amoxicillin isreportedly less effective than ampicillin in the treatment ofbacillary dysentery, presumably because of its greater GIabsorption. Considerable evidence suggests that oral absorptionof α-aminobenzyl–substituted penicillins (e.g.,ampicillin and amoxicillin) and cephalosporins is, at leastin part, carrier mediated, thus explaining their generallysuperior oral activity.Amoxicillin is a fine, white to off-white, crystallinepowder that is sparingly soluble in water. It is available invarious oral dosage forms. Aqueous suspensions are stablefor 1 week at room temperature.

Clinical Use

Isolates should be tested for susceptibility before use, especially for serious infections.
Ear, nose and throat infections other than pharyngitis, which may mask glandular fever
Tracheobronchitis, bronchitis, pneumonia
Genitourinary tract infections, including gonorrhea
Infections of skin and soft tissues due to streptococci and susceptible staphylococci
Helicobacter pylori infection (in combination with a proton pump inhibitor and at least one other antimicrobial agent such as clarithromycin)
Prophylaxis of endocarditis in patients undergoing dental treatment and other procedures

Side effects

Amoxicillin is generally well tolerated, side effects being those common to penicillins, but including non-allergic rashes in patients with glandular fever. As the drug is well absorbed, diarrhea is generally infrequent and rarely sufficiently severe to require withdrawal of treatment.

Amoxicillin Preparation Products And Raw materials

Raw materials

Preparation Products

Amoxicillin Suppliers

Global( 233)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Hebei Jiangkai Trading Co., Ltd
0086-17197824289/17197824028 CHINA 277 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
020-81716319 CHINA 2548 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 CHINA 552 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20229 58
(323) 306-3136
(626) 453-0409 United States 8430 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691 CHINA 295 58

View Lastest Price from Amoxicillin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-02 Amoxicillin Manufacturer; In stock GMP Factory
US $1.00 / KG 1KG High quality manufacturer TOP 3 largest production factory in China Chemwill Asia Co.,Ltd.
2018-09-21 Factory Supply Amoxicillin CAS 26787-78-0 for Medication
US $10.00 / G 10G 99% 100MT Hubei XinRunde Chemical Co., Ltd.
2018-04-11 Amoxicillin
US $1.00 / KG 1KG 99% 10MT Hubei XinRunde Chemical Co., Ltd.

26787-78-0(Amoxicillin)Related Search:

Copyright 2017 © ChemicalBook. All rights reserved