Glycylglycine
- CAS No.
- 556-50-3
- Chemical Name:
- Glycylglycine
- Synonyms
- GLY-GLY;H-GLY-GLY-OH;DIGLYCINE;GLY-GLY-OH;N-GLYCYLGLYCINE;2-(2-aMinoacetaMido)acetic acid;2-[(2-Aminoacetyl)amino]acetic acid;Gly2;y-GL;Gly-Gl
- CBNumber:
- CB3704259
- Molecular Formula:
- C4H8N2O3
- Molecular Weight:
- 132.12
- MDL Number:
- MFCD00008130
- MOL File:
- 556-50-3.mol
- MSDS File:
- SDS
| Melting point | 220-240 °C (dec.) |
|---|---|
| Boiling point | 267.18°C (rough estimate) |
| Density | 1.5851 (rough estimate) |
| vapor pressure | 0.058Pa at 20-50℃ |
| refractive index | 1.4880 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Solid |
| pka | 3.139(at 25℃) |
| color | White |
| PH | 4.5-6.0 (20℃, 1M in H2O) |
| PH Range | 7.5 - 8.9 |
| Water Solubility | SOLUBLE IN HOT WATER |
| λmax |
λ: 260 nm Amax: 0.075 λ: 280 nm Amax: 0.072 |
| Merck | 14,4503 |
| BRN | 1765223 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | YMAWOPBAYDPSLA-UHFFFAOYSA-N |
| LogP | -0.92 at 25℃ and pH6 |
| CAS DataBase Reference | 556-50-3(CAS DataBase Reference) |
| FDA UNII | 10525P22U0 |
| NIST Chemistry Reference | N-Glycylglycine(556-50-3) |
| EPA Substance Registry System | Glycylglycine (556-50-3) |
Glycylglycine price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 50199 | Gly-Gly BioUltra, ≥99.5% (NT) | 556-50-3 | 10g | $77 | 2023-01-07 | Buy |
| Sigma-Aldrich | 50199 | Gly-Gly BioUltra, ≥99.5% (NT) | 556-50-3 | 50g | $291 | 2023-01-07 | Buy |
| TCI Chemical | G0124 | Glycylglycine >99.0%(T) | 556-50-3 | 25g | $34 | 2023-01-07 | Buy |
| TCI Chemical | G0124 | Glycylglycine >99.0%(T) | 556-50-3 | 100g | $106 | 2023-01-07 | Buy |
| Alfa Aesar | A10523 | Glycylglycine, 99% | 556-50-3 | 25g | $44.2 | 2021-12-16 | Buy |
Glycylglycine Chemical Properties,Uses,Production
Chemical Properties
White crystals
Uses
Glycylglycine is as a buffering reagent and also used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. It is also employed as a practical buffer with a buffering range of 7.5 - 8.9 (at 25°C). Valuable agent for experiments investigating peptide transport and absorption.
Definition
ChEBI: A dipeptide formed from glycine residues.
Synthesis Reference(s)
Journal of the American Chemical Society, 75, p. 5323, 1953 DOI: 10.1021/ja01117a053
Biochem/physiol Actions
Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.
Purification Methods
Crystallise glycylglycine from aqueous 50% EtOH or water at 50-60o by addition of EtOH. Dry it at 110o. It sublimes at 190-200o/0.3mm with 30% recovery [Gross & Gradsky J Am Chem Soc 77 1678 1955, King J Am Chem Soc 79 6153 1957]. [Beilstein 4 IV 2459.]
Glycylglycine Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52877 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29810 | 60 |
| Henan DaKen Chemical CO.,LTD. | +86-371-66670886 | info@dakenchem.com | China | 18266 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21975 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 31813 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29922 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22973 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5911 | 58 |
View Lastest Price from Glycylglycine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-04-19 | Glycylglycine
556-50-3
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Crovell Biotech Co Ltd | |
 |
2023-04-18 | Glycylglycine
556-50-3
|
US $30.00-10.00 / kg | 10kg | 99% | 100000kg | Hebei Crovell Biotech Co Ltd | |
 |
2023-02-10 | Glycylglycine
556-50-3
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- Glycylglycine
556-50-3
- US $5.00-2.00 / KG
- 99%
- Hebei Crovell Biotech Co Ltd
-
- Glycylglycine
556-50-3
- US $30.00-10.00 / kg
- 99%
- Hebei Crovell Biotech Co Ltd
-
- Glycylglycine
556-50-3
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.