6-THIOGUANOSINE
- CAS No.
- 85-31-4
- Chemical Name:
- 6-THIOGUANOSINE
- Synonyms
- TGR;TRXR3;TXNRD3;sri759;sk18615;MSTP045;PRO4995;SDR23E1;UNQ2435;nsc-29422
- CBNumber:
- CB3722231
- Molecular Formula:
- C10H13N5O4S
- Molecular Weight:
- 299.31
- MDL Number:
- MFCD00005736
- MOL File:
- 85-31-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-Thioguanosine ≥98% | 36539 | 100mg | $63 |
| 6-Thioguanosine ≥98% | 36539 | 250mg | $108 |
| 6-Thioguanosine ≥98% | 36539 | 500mg | $186 |
| 6-Thioguanosine ≥98% | 36539 | 1g | $248 |
| thioredoxin reductase 3 Purifiedbyimmunoaffinitychromatography. | 337092 | 100ul | $885 |
| Melting point | 230-231°C |
|---|---|
| Boiling point | 756.9±70.0 °C(Predicted) |
| Density | 2.18 |
| refractive index | 1.6460 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility |
DMF: 2 mg/ml DMSO: 5 mg/ml |
| form | Solid |
| pka | 13.21±0.70(Predicted) |
| color | Off-white to light yellow |
| InChI | InChI=1S/C10H13N5O4S/c11-10-13-7-4(8(20)14-10)12-2-15(7)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,20)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | OTDJAMXESTUWLO-UUOKFMHZSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=S)N=C2)[C@H](O)[C@@H]1O |
| CAS DataBase Reference | 85-31-4(CAS DataBase Reference) |
| FDA UNII | C558LI0K8P |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Safety Statements | 24/25 | |||||||||
| RTECS | UP0200000 | |||||||||
| HS Code | 29349990 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: 156mg/kg | |||||||||
| NFPA 704 |
|
6-THIOGUANOSINE price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36539 | 6-Thioguanosine ≥98% | 85-31-4 | 100mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 36539 | 6-Thioguanosine ≥98% | 85-31-4 | 250mg | $108 | 2026-04-30 | Buy |
| Cayman Chemical | 36539 | 6-Thioguanosine ≥98% | 85-31-4 | 500mg | $186 | 2026-04-30 | Buy |
| Cayman Chemical | 36539 | 6-Thioguanosine ≥98% | 85-31-4 | 1g | $248 | 2026-04-30 | Buy |
| Usbiological | 337092 | thioredoxin reductase 3 Purifiedbyimmunoaffinitychromatography. | 100ul | $885 | 2026-06-03 | Buy |
6-THIOGUANOSINE Chemical Properties,Uses,Production
Chemical Properties
Tan Powder
Uses
antineoplastic
Definition
ChEBI: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-3H-purine-6-thione is a purine nucleoside.
Purification Methods
Thioguanosine is crystallised (as hemihydrate) from hot H2O (charcoal) and cooled slowly to give tapered prisms. It also crystallises by dissolving in dilute NH3 and acidifying with acetic acid, and then recrystallising from H2O. UV: (pH 4-6) max at 257nm ( 8,820) and 342nm ( 24,800), and (pH 10.4-12.0) max at 252nm ( 14,700) and 319.5nm ( 21,000). [Fox et al. J Am Chem Soc 80 1667 1958, Beilstein 26 III/IV 3927.]
References
[1] J W WEISS H C P. Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine.[J]. Cancer research, 1974, 34 3: 581-587.
[2] MONIQUE AKOACHERE. Identification of an in vivo inhibitor of Bacillus anthracis spore germination.[J]. The Journal of Biological Chemistry, 2007, 282 16: 12112-12118. DOI: 10.1074/jbc.m611432200
[3] D L HILL R F P. Use of Escherichia coli mutants to evaluate purines, purine nucleosides, and analogues.[J]. Antimicrobial Agents and Chemotherapy, 1973, 4 2: 125-132. DOI: 10.1128/aac.4.2.125
[4] N T VETHE S B S Bremer. IMP dehydrogenase basal activity in MOLT-4 human leukaemia cells is altered by mycophenolic acid and 6-thioguanosine.[J]. Scandinavian Journal of Clinical & Laboratory Investigation, 2008, 68 4: 277-285. DOI: 10.1080/00365510701724871
6-THIOGUANOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
6-THIOGUANOSINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NewCan Biotech Limited | +86-571-86912261 19975279805 | sales@newcanbio.com | China | 9985 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28009 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
View Lastest Price from 6-THIOGUANOSINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-02 | 6-Thioguanosine
85-31-4
|
$35.00 | 98.00% | 10g | TargetMol Chemicals Inc. |
-
- 6-Thioguanosine
85-31-4
- $35.00
- 98.00%
- TargetMol Chemicals Inc.
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