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3-Nitrophenol structure
Chemical Name:
Nsc 1551;3-Nitrophe;m-Nitrofenol;M-NITROPHENOL;3-NITROPHENOL;3-nitro-pheno;m-nitro-pheno;Phenol,3-nitro-;Phenol, m-nitro-;meta-Nitrophenol
Molecular Formula:
Formula Weight:
MOL File:

3-Nitrophenol Properties

Melting point:
89-95 °C
Boiling point:
194 °C70 mm Hg(lit.)
1,49 g/cm3
refractive index 
1.5723 (estimate)
Flash point:
storage temp. 
Store at +5°C to +30°C.
13.5g/l insoluble
8.28(at 25℃)
Crystalline Powder
Yellow to brown
PH Range
6.6-8.6 (H2O, 20℃)
Water Solubility 
13.5 g/L (25 ºC)
Major Application
Display device, semiconductor device, sensors, high voltage capacitors, energetic materials, electrolyte batteries, inks, correction fluid, detergent, leak detection method, lubricants, insecticide, food storage, inhibition of amyloidoses, detect bacterialinfection, drugs, material for evaluating dental caries activity
CAS DataBase Reference
554-84-7(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 3-nitro-(554-84-7)
EPA Substance Registry System
Phenol, 3-nitro-(554-84-7)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi
Risk Statements  22-38-41-36/37/38-33-20/21/22
Safety Statements  26-36/37-45-36/37/39-22-28
RIDADR  UN 1663 6.1/PG 3
WGK Germany  3
RTECS  SM1925000
Autoignition Temperature 400 °C
Hazard Note  Harmful/Irritant
HazardClass  6.1
PackingGroup  III
HS Code  29089000
Hazardous Substances Data 554-84-7(Hazardous Substances Data)
Toxicity LD50 orally in mice, rats: 1414, 933 mg/kg, K. C. Back et al., Reclassification of Materials Listed as Transportation Health Hazards (TSA-20-72-3; PB214-270, 1972)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

3-Nitrophenol price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 163031 3-Nitrophenol ReagentPlus , 99% 554-84-7 10g $70.2 2018-11-13 Buy
Sigma-Aldrich 163031 3-Nitrophenol ReagentPlus , 99% 554-84-7 50g $199 2018-11-13 Buy
TCI Chemical N0217 3-Nitrophenol >98.0%(GC) 554-84-7 25g $79 2018-11-22 Buy
TCI Chemical N0217 3-Nitrophenol >98.0%(GC) 554-84-7 100g $220 2018-11-22 Buy
Alfa Aesar A15312 3-Nitrophenol, 98+% 554-84-7 10g $53.9 2018-11-13 Buy

3-Nitrophenol Chemical Properties,Uses,Production

Chemical Properties

yellow to brown crystalline powder


3-Nitrophenol is a chemical reagent used in various organic syntheses. Used in the synthesis of RAGE inhibitors via the etherification of phenols. Also used in the synthesis of kinase inhibitors again st epidermal growth factor receptor T790M mutation.


ChEBI: A member of the class of 3-nitrophenols that is phenol in which one of the hydrogens that is meta to the hydroxy group has been replaced by a nitro group.


As indicator in 0.3% solution in 50% alcohol. pH: 6.8 colorless, 8.6 yellow.

General Description

Colorless to pale yellow crystalline solid. Sinks in and mixes with water.

Air & Water Reactions

Water insoluble.

Reactivity Profile

3-Nitrophenol is a light-yellow, crystalline material, toxic and irritant. When heated to decomposition 3-Nitrophenol emits toxic fumes of oxides of nitrogen [Lewis, 3rd ed., 1993, p. 941]. Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases.


Toxic by ingestion.

Health Hazard

INHALATION: Inhalation or ingestion causes headaches, drowsiness, nausea, and blue color in lips, ears, and finger nails (cyanosis). EYES: Contact with eyes causes irritation. SKIN: Can be absorbed through intact skin to give same symptoms as for inhalation.

Fire Hazard

Special Hazards of Combustion Products: Dangerous toxic fumes of NO x

Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. Moderately toxic by skin contact. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also other nitrophenol entries.

Purification Methods

Crystallise 3-nitrophenol from water, CHCl3, CS2, EtOH or pet ether (b 80-100o), and dry it under vacuum over P2O5 at room temperature. It can also be distilled at low pressure. The 4-nitrobenzoate had m 174o (from EtOH). [Beilstein 6 IV 1269.]

3-Nitrophenol Preparation Products And Raw materials

Raw materials

Preparation Products

3-Nitrophenol Suppliers

Global( 198)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
AB PharmaTech,LLC
323-480-4688 United States 991 55
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19953 60
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20229 58
Zhejiang ZETian Fine Chemicals Co. LTD
+86-18957127338 CHINA 1584 58
career henan chemical co
+86-371-86658258 CHINA 19997 58
Hangzhou Disynthesis Chemical Technology Co., Ltd. +86 (571) 8819-4596/ 15558156576, QQ:1695750899
+86 (571) 8819-9298; China 100 55
Tianshui YiYao Chemical Co., Ltd. 0938-8493022
0938-8493022 China 1008 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76

View Lastest Price from 3-Nitrophenol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-25 3-Nitrophenol
US $100.00 / KG 1KG 99% 20kg career henan chemical co

3-Nitrophenol Spectrum

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