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Rebaudioside A

CAS No.
58543-16-1
Chemical Name:
Rebaudioside A
Synonyms
REBAUDIOSIDE;Steviol Glycoside;Reb A;4G-S;Rebiana;Reb-A 97;Pure Via;Glycoside X;Lebaldide A;Glycoside A3
CBNumber:
CB3736050
Molecular Formula:
C44H70O23
Molecular Weight:
967.01
MDL Number:
MFCD02183463
MOL File:
58543-16-1.mol
MSDS File:
SDS
Last updated:2023-06-28 18:16:08

Rebaudioside A Properties

Melting point 235°C(lit.)
Boiling point 1102.8±65.0 °C(Predicted)
Density 1.59±0.1 g/cm3(Predicted)
vapor pressure 0-1198Pa at 20-50℃
FEMA 4601 | REBAUDIOSIDE A
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
pka 12.51±0.70(Predicted)
color White to Off-White
optical activity [α]/D -33.0±3.0°, c = 1% in H2O
BRN 6470556
Stability Hygroscopic
LogP -1-2.61 at 20-25℃ and pH7
Substances Added to Food (formerly EAFUS) REBAUDIOSIDE A
FDA UNII B3FUD0528F

SAFETY

Risk and Safety Statements

Safety Statements  24/25
WGK Germany  3
RTECS  NZ8174800
HS Code  29389090

Rebaudioside A price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL80067 Rebaudioside A phyproof? Reference Substance 58543-16-1 20MG $288 2024-03-01 Buy
Sigma-Aldrich 1600121 Rebaudioside A United States Pharmacopeia (USP) Reference Standard 58543-16-1 500mg $706 2024-03-01 Buy
Sigma-Aldrich 01432 Rebaudioside A ≥96% (HPLC) 58543-16-1 10g $154 2024-03-01 Buy
TCI Chemical R0095 Rebaudioside A >98.0%(HPLC) 58543-16-1 5g $77 2024-03-01 Buy
TCI Chemical R0095 Rebaudioside A >98.0%(HPLC) 58543-16-1 25g $269 2024-03-01 Buy
Product number Packaging Price Buy
PHL80067 20MG $288 Buy
1600121 500mg $706 Buy
01432 10g $154 Buy
R0095 5g $77 Buy
R0095 25g $269 Buy

Rebaudioside A Chemical Properties,Uses,Production

Description

Rebaudioside A is a natural non-caloric sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. In a two bottle preference test, mice drink more water containing rebaudioside A than unsweetened water, though saccharin-sweetened water is still preferred. Rebaudioside A is metabolized by gut microbiota to steviol , a compound whose safety is widely studied. Consumption of rebaudioside A formulations by pre-diabetic patients did not increase fasting or 2 hour plasma glucose levels or insulin levels.

Chemical Properties

White powder

Uses

Rebaudioside A is a glycoside from the stevia plant. Rebaudioside A is used as a sweetener with sweetness about 300 times that of sugar with negligible effect on blood glucose. As a result, Rebaudiosi de A is known for its application in treatment of many diseases like diabetes, high blood pressure and weight loss in some places. It is used as a food additive and in dietary supplements.

Uses

natural sweetener to diabetics and others on carbohydrate-controlled diets

Uses

Rebaudioside A is a natural, highly processed calorie free sweetener obtained from the leaves of the plant stevia rebaudiana bertoni. it is a steviol glycoside in which the steviol’s carboxyl and hydroxyl hydrogen atom is replaced with glucose, it has three linked glucose molecules at the hydroxyl site. rebaudiana (reb a) is 300–400 times sweeter than sugar and the least bitter of the glycosides. it is ph and heat stable with good solubility in water. uses include beverages, table top sweetener, general foods. it is also termed reb a, stevia extract, stevia.

Definition

Rebaudioside A is a rebaudioside that is rubusoside in which the hydroxy groups at positions 3 and 4 of the beta-D-glucopyranosyloxy group at the 13alpha position have both been converted to the corresponding beta-D-glucopyranoside. It has a role as a sweetening agent. It is a beta-D-glucoside, a tetracyclic diterpenoid and a rebaudioside. It derives from a rubusoside and a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->3)]-beta-D-Glcp.

benefits

Zero calories
No carbohydrate
Does not raise blood glucose or insulin levels (Zero Index Glycemic), safe for people with diabetes
Keto, Vegan, and Gluten-Free

Biological Activity

Rebaudioside A is a natural non-caloric sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. In a two bottle preference test, mice drink more water containing rebaudioside A than unsweetened water, though saccharin-sweetened water is still preferred. Rebaudioside A is metabolized by gut microbiota to steviol, a compound whose safety is widely studied. Consumption of rebaudioside A formulations by pre-diabetic patients did not increase fasting or 2 hour plasma glucose levels or insulin levels.

Safety

High-purity (95% minimum) of individual or combined steviol glycosides can be considered as GRAS (Generally Recognized as Safe) by the FDA. For example, FDA had no questions regarding Guilin Layn's conclusion that its reb A (≥97% by weight (w/w)) is GRAS as a table top sweetener and as a general purpose sweetener in foods, excluding meat and poultry products and infant formulas.
Its safety has also been approved by the EFSA, JECFA, FSANZ and other authorities.

57817-89-7
57-50-1
58543-16-1
Synthesis of Rebaudioside A from Stevioside and Sucrose

Rebaudioside A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 269)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58

View Lastest Price from Rebaudioside A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rebaudioside A; stevia?rebaudiana extract pictures 2024-04-23 Rebaudioside A; stevia?rebaudiana extract
58543-16-1
US $0.00 / KG 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Rebaudioside A pictures 2023-06-29 Rebaudioside A
58543-16-1
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
stock Rebaudioside A 58543-16-1 pictures 2022-02-14 stock Rebaudioside A 58543-16-1
58543-16-1
US $60.00 / mg 20mg ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
  • Rebaudioside A pictures
  • Rebaudioside A
    58543-16-1
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
(4α)-13-[(2-O-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]kaur-6-en-8-oic acid β-D-glucopyranosyl ester Rebaudioside A (300 mg) REBAUDIOSIDE A(rebiana)(RG) (4α)-13-[(O-β-D-Glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]kaur-16-en-18-oic Acid β-D-Glucopyranosyl Ester 4G-S Glycoside A3, froM Stevia rebaudiana Glycoside X Pure Via Reb-A 97 Rebiana Sooolite!-Pure Sweetener 4G-S Rebaudioside A, froM Steviarebaudiana Rebaudioside A (500 mg) (4α)-13-[(2-O-β-D-glucopyranosyl-3-O-β-D­ glucopyranosyl-β-D-glucopyranosyl)-oxy]kaur-6-en-8-oic acid β-D­ STEVIOSIDE A3 MONOGLYCOSYLSTEVIOSIDE REBAUDIOSIDE, 60% RebaudiosideA(enzymaticallymodified) REBAUDIOSIDE A STANDARD (4R)-13-[(2-O-β-D-Glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid β-D-glucopyranosyl ester stock Rebaudioside A 58543-16-1 Rebaudioside A 50% (RA50) Rebaudioside A, 97%, from Steviarebaudiana A Rebaudioside A > Glycoside A3 Kaur-16-en-18-oic acid, 13-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]-, β-D-glucopyranosyl ester, (4α)- REBAUDIOSIDE A USP/EP/BP Kaur-16-en-18-oic acid,13-[(O-b-D-glucopyranosyl-(1?2)-O-[b-D-glucopyranosyl-(1?3)]-b-D-glucopyranosyl)oxy]-, b-D-glucopyranosyl ester, (4a)- Rebaudioside A Lebaldide A Steviol Glycoside Reb A REBAUDIOSIDE (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (4R,4aS,6aR,9S,11aR,11bS)-9-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylate Lepidoside A Stevia diglycoside/Reb A 58543-16-1 C44H70O23 Miscellaneous Natural Products chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract