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TOFISOPAM

CAS No.
22345-47-7
Chemical Name:
TOFISOPAM
Synonyms
SERIEL;Tosopam;EGYT 341;grandaxin;tofizopam;TOFISOPAM;Tofisopam, >=99%;TOFISOPAM 22345-47-7;7-CHLORO-1-METHYL-5-PHENYL-1,5-BENZODIAZEPINE-2,4-DIONE;-5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine
CBNumber:
CB3738807
Molecular Formula:
C22H26N2O4
Molecular Weight:
382.45
MDL Number:
MFCD00823171
MOL File:
22345-47-7.mol
Last updated:2023-09-04 15:51:00

TOFISOPAM Properties

Melting point 155-159°C
Boiling point 509.61°C (rough estimate)
Density 1.2098 (rough estimate)
refractive index 1.6500 (estimate)
solubility DMSO: ~14 mg/mL
pka 7.29±0.40(Predicted)
form solid
color white
λmax 310nm(MeOH)(lit.)
Merck 14,9503
Stability Hygroscopic
FDA UNII UZC80HAU42
ATC code N05BA23

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H400
Precautionary statements  P273-P301+P312+P330
Hazard Codes  Xn,N
Risk Statements  22-50
Safety Statements  60-61
RIDADR  UN 3077 9/PG 3
WGK Germany  2
RTECS  DE9540000
HS Code  2933.99.8290
HazardClass  6.1(b)
PackingGroup  III
NFPA 704
0
2 0

TOFISOPAM price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T8200 Tofisopam ≥98% (HPLC), solid 22345-47-7 10mg $176 2024-03-01 Buy
Sigma-Aldrich T8200 Tofisopam ≥98% (HPLC), solid 22345-47-7 50mg $558 2024-03-01 Buy
TCI Chemical T3509 Tofisopam >98.0%(HPLC) 22345-47-7 50mg $84 2024-03-01 Buy
TCI Chemical T3509 Tofisopam >98.0%(HPLC) 22345-47-7 250mg $253 2024-03-01 Buy
Cayman Chemical 22026 Tofisopam ≥95% 22345-47-7 1mg $73 2024-03-01 Buy
Product number Packaging Price Buy
T8200 10mg $176 Buy
T8200 50mg $558 Buy
T3509 50mg $84 Buy
T3509 250mg $253 Buy
22026 1mg $73 Buy

TOFISOPAM Chemical Properties,Uses,Production

Originator

Grandaxine,Ozothine,France,1975

Uses

Tofisopam is a reagent used in preparation of allosteric ligands for pharmacological dark receptors GPR68 and GPR65. An anticonvulsant.

Definition

ChEBI: Tofisopam is an organic molecular entity.

Manufacturing Process

A mixture of 38.6 g (0.1 mol) of 3,4,3',4'-tetramethoxy-6-(α-acetopropyl)- benzophenone, 5.5 g (0.11 mol) of 100% hydrazine hydrate or 3.52 g (0.11 mol) of hydrazine, and 500 ml of absolute ethanol is boiled for 5 hours. After adding 100 ml of benzene, 400 ml of solvent mixture is distilled off from the reaction mixture by slow boiling for 3 hours. After cooling for 8 hours, 19 g of 5H-2,3-benzodiazepine derivative are separated from the residue as small, white crystals. The melting point is 133°C to 136°C (after recrystallizing from absolute ethanol, 136°C)

Therapeutic Function

Tranquilizer

TOFISOPAM Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 104)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998 sales@czwytech.com CHINA 906 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17368 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58
Shijiazhuang Tongyang Import and Export Co., LTD
18031361688; admin@sjztongyang.com China 987 58
changzhou huayang technology co., ltd
+8615250961469 2571773637@qq.com China 9821 58

View Lastest Price from TOFISOPAM manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TOFISOPAM  pictures 2021-08-11 TOFISOPAM
22345-47-7
US $10.00 / KG 1g 99 100kg/kg Shijiazhuang tongyang Import and Export Co., LTD
TOFISOPAM 22345-47-7 pictures 2019-07-31 TOFISOPAM 22345-47-7
22345-47-7
US $1.00 / g 1g 99% 300 Ton/Tons per Month china raw material pharmaceutical Tofisopam Cangzhou Wanyou New Material Technology Co.,Ltd
TOFISOPAM pictures 2019-07-06 TOFISOPAM
22345-47-7
US $14.00 / KG 1KG 98% 50KG Career Henan Chemical Co
  • TOFISOPAM  pictures
  • TOFISOPAM
    22345-47-7
  • US $10.00 / KG
  • 99
  • Shijiazhuang tongyang Import and Export Co., LTD
  • TOFISOPAM pictures
  • TOFISOPAM
    22345-47-7
  • US $14.00 / KG
  • 98%
  • Career Henan Chemical Co

TOFISOPAM Spectrum

TOFISOPAM 7,8-DIMETHOXY-1-(3,4-DIMETHOXYPHENYL)-5-ETHYL-4-METHYL-5H-2,3-BENZODIAZEPINE 1-(3,4-Dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine 5H-2,3-Benzodiazepine, 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl- (8CI, 9CI) tofizopam 7-CHLORO-1-METHYL-5-PHENYL-1,5-BENZODIAZEPINE-2,4-DIONE EGYT 341, Seriel, 7,8-Dimethoxy-1-(3,4-dimethoxyphenyl)-5-ethyl-4-methyl-5H-2,3-benzodiazepine EGYT 341 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-3-benzodiazepine grandaxin Tofisopam, >=99% -5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine SERIEL 1-[3,4-Bis(methyloxy)phenyl]-5-ethyl-4-methyl-7,8-bis(methyloxy)-5H-2,3-benzodiazepine 1-(3,4-DiMethoxyphenyl)-5-ethyl-7,8-diMethoxy-4-Methyl-5H-2,3-benzodiazepine (TofisopaM) 1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine Tosopam TOFISOPAM 22345-47-7 5H-2,3-Benzodiazepine, 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl- TofisopamQ: What is Tofisopam Q: What is the CAS Number of Tofisopam Q: What is the storage condition of Tofisopam Q: What are the applications of Tofisopam 22345-47-7 C22H26N2O4