Ethyl methyldopate hydrochloride
- CAS No.
- 2508-79-4
- Chemical Name:
- Ethyl methyldopate hydrochloride
- Synonyms
- METHYLDOPATE HCL;METHYLDOPAETHYLHCL;Ethyl ester hydrochloride;METHYLDOPATE HYDROCHLORIDE;QSRVZCCJDKYRRF-YDALLXLXSA-N;Aldomet Ester hydrochloride;methyldopa ethyl hydrochloride;Ethyl methyldopa hydrochloride;ethyl methyldopate hydrochloride;Methyldopate Hydrochloride (200 mg)
- CBNumber:
- CB3746806
- Molecular Formula:
- C12H18ClNO4
- Molecular Weight:
- 275.73
- MDL Number:
- MFCD07787407
- MOL File:
- 2508-79-4.mol
| FDA UNII | 7PX435DN5A |
|---|
Ethyl methyldopate hydrochloride price More Price(1)
Ethyl methyldopate hydrochloride Chemical Properties,Uses,Production
Uses
Ethyl methyldopate hydrochloride is Antihypertensive.
brand name
Aldomet (Merck).
General Description
Methyldopatehydrochloride, L-3-(3,4-dihydroxyphenyl)-2-methylalanineethyl ester hydrochloride (Aldomet ester hydrochloride), α-methyldopa, lowers blood pressure by inhibitingthe outflow of sympathetic vasoconstrictor impulses fromthe brain. Early studies had suggested that the hypotensiveaction of α-methyldopa was a result of the peripheral propertiesof the drug as a decarboxylase inhibitor or a falsetransmitter.
Clinical Use
Ethyl methyldopate hydrochloride is used as a step 2 agent and is recommendedfor patients with high blood pressure who are not responsiveto diuretic therapy alone. Ethyl methyldopate hydrochloride, suitable for oral use,is a zwitterion and is not soluble enough for parenteral use.The problem was solved by making the ester, leaving theamine free to form the water-soluble hydrochloride salt. It issupplied as a stable, buffered solution, protected with antioxidantsand chelating agents.
Ethyl methyldopate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18456 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696; | info@hanhongsci.com | China | 42982 | 64 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |