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NEUROPEPTIDE FF

NEUROPEPTIDE FF Structure
NEUROPEPTIDE FF structure
CAS No.
99566-27-5
Chemical Name:
NEUROPEPTIDE FF
Synonyms
NPFF;NPAF;ninamide;F-8-F-NH2;FLFQPQRF-NH2;NEUROPEPTIDE FF;Neuropeptide FF TFA;Neuropeptide FF (cattle);Neuropeptide FF F-8-F-NH2;NEUROPEPTIDE FF USP/EP/BP
CBNumber:
CB3750458
Molecular Formula:
C54H76N14O10
Molecular Weight:
1081.27
MDL Number:
MFCD00076704
MOL File:
99566-27-5.mol
Last updated:2023-06-30 15:45:59
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NEUROPEPTIDE FF Properties

storage temp. −20°C
solubility Water: 1 mg/ml
form Solid
Water Solubility Soluble to 0.50 mg/ml in water.

SAFETY

Risk and Safety Statements

WGK Germany  3

NEUROPEPTIDE FF price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J66509 Neuropeptide FF 99566-27-5 1mg $58.2 2023-06-20 Buy
Cayman Chemical 24548 Neuropeptide FF (trifluoroacetate salt) ≥95% 99566-27-5 1mg $158 2024-03-01 Buy
Tocris 3137 Neuropeptide FF 99566-27-5 1 $162 2021-12-16 Buy
Usbiological 027103 Neuropeptide FF 99566-27-5 96Tests $864 2021-12-16 Buy
Usbiological 027102 Neuropeptide FF 99566-27-5 96Tests $879 2021-12-16 Buy
Product number Packaging Price Buy
J66509 1mg $58.2 Buy
24548 1mg $158 Buy
3137 1 $162 Buy
027103 96Tests $864 Buy
027102 96Tests $879 Buy

NEUROPEPTIDE FF Chemical Properties,Uses,Production

Description

Neuropeptide FF (NPFF) is a peptide expressed in the brain and spinal cord that shares a precursor protein with neuropeptide AF. NPFF is expressed primarily in the posterior pituitary, hypothalamus, and medulla. It is an agonist at NPFF1 and NPFF2 receptors (Kis = 2.82 and 0.21 nM, respectively, for human recombinant receptors) that inhibits forskolin-induced cAMP production in CHO cells (EC50s = 236 and 2.3 nM, respectively). NPFF activates parvocellular neurons in the paraventricular nucleus (PVN) of the hypothalamus to stimulate oxytocin release from their projections in the brain stem, thereby regulating baroreflex control of heart rate. However, it inhibits magnocellular PVN neurons by enhancing GABAergic input. It is also found in plasma and exogenous administration briefly increases mean arterial pressure (MAP) by 40 mm Hg in rats, an effect that is only partially blocked by the norepinephrine competitor guanethidine and the α1-adrenergic receptor antagonist prazosin . NPFF has anti-opioid effects in rodent models, inhibiting morphine-induced analgesia and inducing abstinence in morphine-tolerant rats. It also inhibits acquisition of conditioned place preference to cocaine in rats when administered at doses of 10 and 20 nmol.

Uses

Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects.

storage

Store at -20°C

NEUROPEPTIDE FF Preparation Products And Raw materials

Raw materials

Preparation Products

NEUROPEPTIDE FF Suppliers

Global( 100)Suppliers
Supplier Tel Email Country ProdList Advantage
Cellmano Biotech Limited 		0551-65326643 18156095617 info@cellmano.com China 999 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 29474 58
BOC Sciences 		+16314854226 inquiry@bocsci.com United States 19743 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Go Top Peptide Biotech 		0571-88211921 sales1@gotopbio.com CHINA 2609 58
Chengdu Youngshe Chemical Co., Ltd. 		+8618108235634 Cecilia@youngshechem.com China 2345 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
ZHEJIANG JIUZHOU CHEM CO., LTD 		+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com China 20000 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49999 58
Supplier Advantage
Cellmano Biotech Limited 		58
career henan chemical co 		58
Dideu Industries Group Limited 		58
BOC Sciences 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Hangzhou Go Top Peptide Biotech 		58
Chengdu Youngshe Chemical Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
ZHEJIANG JIUZHOU CHEM CO., LTD 		58
GIHI CHEMICALS CO.,LIMITED 		58

View Lastest Price from NEUROPEPTIDE FF manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NEUROPEPTIDE FF pictures 2020-03-06 NEUROPEPTIDE FF
99566-27-5
 US $1.00 / g 1g ≥98% g/kg/Ton Career Henan Chemical Co

99566-27-5(NEUROPEPTIDE FF)Related Search:

NEUROPEPTIDE AF (HUMAN) NEUROPEPTIDE Y (13-36), PORCINE SYNTHETI C >97% PANCREATIC POLYPEPTIDE, RAT SUBSTANCE P (2-11) SUBSTANCE P (6-11)
Substance P (1-7)(TFA) substance P (3-11) (LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT) Calcitonin Gene Related Peptide (CGRP) (83-119), rat TFA Galanin (1-16), mouse, porcine, rat TFA
NEUROPEPTIDE F GALANIN, PORCINE GLY-LEU-MET-NH2 H-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2 H-LEU-PRO-GLY-LEU-PRO-SER-ALA-ALA-SER-SER-GLU-ASP-ALA-GLY-GLN-SER-NH2
SUBSTANCE P (1-9) SUBSTANCE P NEUROPEPTIDE Y (HUMAN, RAT)

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PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE AMIDE PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2 NPFF NEUROPEPTIDE FF H-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2 F-8-F-NH2 ninamide phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylala POTASSIUM FERROCYANIDE TRIHYDRATE*ACS RE AGENT Neuropeptide FF F-8-F-NH2 phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2 Neuropeptide FF F-8-F-NH2, NPFF, F-8-F-aMide F-8-F-NH2, NPFF, F-8-F-aMide ANTI-NPFF (C-TERM) antibody produced in rabbit FMRFamide-related peptides NPAF Neuropeptide FF (trifluoroacetate salt) L-Phenylalaninamide, L-phenylalanyl-L-leucyl-L-phenylalanyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-arginyl- Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide >=95% (HPLC) NEUROPEPTIDE FF USP/EP/BP Neuropeptide FF (cattle) Rabbit Anti-NPFF antibody FLFQPQRF-NH2 Neuropeptide FF trifluoroacetate salt (NPFF) Neuropeptide FF TFA 99566-27-5 C54H76N14O10 BioChemical Amino Acids and Peptides Biochemicals and Reagents Other Peptides Peptides Peptide