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Amrinone

Amrinone
Amrinone structure
CAS No.
60719-84-8
Chemical Name:
Amrinone
Synonyms
inocor;Vesistol;Cartonic;AMRINONE;Wincoram;win40680;Amirinone;awd08-250;INAMRINONE;cordemcura
CBNumber:
CB3774164
Molecular Formula:
C10H9N3O
Formula Weight:
187.2
MOL File:
60719-84-8.mol

Amrinone Properties

Melting point:
294-297°C (dec.)
Boiling point:
321.94°C (rough estimate)
Density 
1.2025 (rough estimate)
refractive index 
1.4830 (estimate)
storage temp. 
2-8°C
Water Solubility 
Insoluble in water or chloroform. Slightly soluble in acetic acid or DMF. Soluble in DMSO
CAS DataBase Reference
60719-84-8(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,Xn
Risk Statements  25-36/37/38-20/21/22
Safety Statements  28-45-36-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  DW2500000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29333999
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P321 Specific treatment (see … on this label).
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.

Amrinone price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A4056 Amrinone 60719-84-8 1g $180 2018-11-20 Buy
Sigma-Aldrich 1034308 Amrinone United States Pharmacopeia (USP) Reference Standard 60719-84-8 500mg $338.1 2018-11-20 Buy
Alfa Aesar J62655 Amrinone, 98% 60719-84-8 1g $192 2018-11-13 Buy
Alfa Aesar J62655 Amrinone, 98% 60719-84-8 250mg $57.6 2018-11-13 Buy
Cayman Chemical 23898 Amrinone ≥98% 60719-84-8 500mg $67 2018-11-19 Buy

Amrinone Chemical Properties,Uses,Production

Description

Amrinone is a positive inotropic agent useful in the management of severe congestive heart failure. It is effective even in unresponsive, fully digitalized patients.

Chemical Properties

Crystalline Solid

Originator

Sterling-Winthrop (USA)

Uses

A selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. Cardiotonic

Uses

analgesic, antipyretic, antiinflammatory

brand name

Inocor (Sterling Winthrop).

General Description

During normal heart function, cAMP performsimportant roles in regulating intracellular calcium levels.That is, certain calcium channels and storage sites forcalcium must be activated by cAMP-dependant protein kinases.Because cAMP plays an indirect role in the contractilityprocess, agents that inhibit its degradation will providemore calcium for cardiac contraction. One phosphodiesteraseenzyme that is involved in the hydrolysis of myocardiumcAMP is F-III. Amrinone, 5-amino (3,4 -dipyridin)-6 1 (H)-one (Inocor), possesses positive isotropic effects as aresult of its ability to inhibit this phosphodiesterase. In 1999,the USP Nomenclature Committee and the United StatesAdopted Names (USAN) Council approved changing thenonproprietary name and the current official monograph titleof amrinone to inamrinone. This change in nomenclature wasa result of amrinone being confused with amiodarone becauseof the similarity of the names. This was reported to cause confusionbetween the products that led to medication errors,some of which resulted in serious injury or death.

Amrinone Preparation Products And Raw materials

Raw materials

Preparation Products


Amrinone Suppliers

Global( 136)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20229 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418
001-617-206-9595 sales@chemreagents.com United States 9943 62
Shanghai Longsheng chemical Co.,Ltd. 021-58099637,58099652,58099650,58099609 To 8009,8068; 13585536065,QQ:975986869
0086-21-33191781 sales@shlschem.com; bin.wu@shlschem.com;xianjun.hong@shlschem.com China 9846 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32492 50

View Lastest Price from Amrinone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Amrinone
60719-84-8
US $1.00 / KG 1G 98% 100KG career henan chemical co

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