VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
- CAS No.
- 106021-96-9
- Chemical Name:
- VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
- Synonyms
- Sclavo peptide;IL-1B (163-171) (HUMAN);interleukin-1beta(163-171;IL-1BETA (163-171) (HUMAN);INTERLEUKIN-1B (163-171) (HUMAN);b-Interleukin I (163-171), human;β-Interleukin I (163-171), human;Interleukin-1β (163-171) (human);β-Interleukin I (163-171), human;VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
- CBNumber:
- CB3776638
- Molecular Formula:
- C39H64N12O19
- Molecular Weight:
- 1004.99
- MDL Number:
- MFCD00076554
- MOL File:
- 106021-96-9.mol
- MSDS File:
- SDS
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | A1026 | β-InterleukinI(163-171),human | 106021-96-9 | 5mg | $60 | 2021-12-16 | Buy |
| ApexBio Technology | A1026 | β-InterleukinI(163-171),human | 106021-96-9 | 10mg | $100 | 2021-12-16 | Buy |
| ApexBio Technology | A1026 | β-InterleukinI(163-171),human | 106021-96-9 | 25mg | $140 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0009164 | BETA-INTERLEUKIN I(163-171)-HUMAN 95.00% | 106021-96-9 | 1MG | $612.15 | 2021-12-16 | Buy |
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Chemical Properties,Uses,Production
Biological Activity
β-interleukin i (163-171), human(c39h64n12o19), a peptide with the sequence val-gln-gly-glu-glu-ser-asn-asp-lys, mw= 1005. interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). interleukin 1 alpha and interleukin 1 beta (il-1 alpha and il-1 beta) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis.interleukin-1 beta (il-1β) also known as catabolin, is a cytokine protein that in humans is encoded by the il1b gene. il-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). cytosolic thiol protease cleaves the product to form mature il-1β. il-1β is a member of the interleukin 1 cytokine family. this cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.figure1 formula of b-interleukin i (163-171), humanfigure2 structure of b-interleukin i
Biochem/physiol Actions
IL1B (interleukin 1 β) is an immune-activating cytokine. In presence of infection or cell stress, it gets converted into active mature form.
References
1. Contassot E, Beer HD, French LE (2012). "Interleukin-1, inflammasomes, autoinflammation and the skin". Swiss Med Wkly 142: w135902. Matzinger P (2012). "The evolution of the danget theory. Interview by Lauren Constable, Commissioning Editor". Expert Rev Clin Immunol 8 (4): 311-7.3. Sahoo M, Ceballos-Olvera I, del Barrio L, Re F (2011). "Role of the inflammasome, IL-1β, and IL-18 inbacterial infections". ScientificWorldJournal 11: 2037-50.
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Preparation Products And Raw materials
Raw materials
Preparation Products
VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696; | info@hanhongsci.com | China | 42982 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| ApexBio Technology LLC | +1-832-696-8203 | info@apexbt.com | United States | 477 | 60 |