ANTI-RAB7

CAS No.
Chemical Name:
ANTI-RAB7
Synonyms
ANTI-RAB7;Anti-MGC9726;Anti-MGC16212;ANTI-RAS-RELATED PROTEIN RAB7;Anti-Rab7 antibody produced in rabbit;Anti-RAB7B, member RAS oncogene family;Anti-RAB7B (126-140) antibody produced in rabbit;Monoclonal Anti-RAB7B antibody produced in mouse
CBNumber:
CB3785942
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD08705509
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

ANTI-RAB7 Properties

storage temp. -20°C
form buffered aqueous solution

ANTI-RAB7 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R4779 Anti-Rab7 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 200μL $566 2023-06-20 Buy
Sigma-Aldrich WH0338382M1 Monoclonal Anti-RAB7B antibody produced in mouse clone 3B3, purified immunoglobulin, buffered aqueous solution 100μG $503 2023-01-07 Buy
Product number Packaging Price Buy
R4779 200μL $566 Buy
WH0338382M1 100μG $503 Buy

ANTI-RAB7 Chemical Properties,Uses,Production

Uses

Anti-Rab7 antibody can be used in indirect immunofluorescence and immunoblotting.

General Description

Rab7 is a member of the Rab family of small guanosine triphosphatases (GTPases). Rab proteins contain conserved regions involved in guanine nucleotide binding, and hypervariable COOH-terminal domains with a cysteine motif, implicated in subcellular targeting. Each Rab protein shows a characteristic subcellular distribution. The antibody is affinity-purified using the immunizing peptide immobilized on agarose.

Biochem/physiol Actions

Rab family of small guanosine triphosphatases (GTPases) are central regulators of membrane trafficking between the different subcellular compartments of the eukaryotic cell. Their regulatory capacity depends on their ability to cycle between the GDP-bound inactive and GTP-bound active states. Conversion from one state to the other is regulated by GDP/GTP exchange factors (GEPs), GDP dissociation inhibitors (GDIs) and GTPase-activating proteins (GAPs). Activation of a Rab protein is coupled to its association with intracellular membranes, allowing it to recruit downstream effector proteins to the cytoplasmic surface of a subcellular compartment. Through their effector proteins, Rab GTPases regulate vesicle formation, actin- and tubulin-dependent vesicle movement, and membrane fusion. Rab7 is also involved in the maturation of late autophagic vacuoles. Among Rab7 effectors are RILP (Rab-interacting lysosome protein) that controls late endosomal and lysosomal transport by mediating the recruitment of dynein/dynactin motors, Rabring7 (Rab7- interacting ring finger protein),(10) and the hVPS34/p150 complex. Anti-Rab7 may be used as a marker for late endosomes.

ANTI-RAB7 Preparation Products And Raw materials

Raw materials

Preparation Products

ANTI-RAB7 Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Monoclonal Anti-RAB7B antibody produced in mouse Anti-Rab7 antibody produced in rabbit Anti-RAB7B (126-140) antibody produced in rabbit ANTI-RAS-RELATED PROTEIN RAB7 ANTI-RAB7 Anti-MGC16212 Anti-MGC9726 Anti-RAB7B, member RAS oncogene family