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DPO-1

CAS No.
43077-30-1
Chemical Name:
DPO-1
Synonyms
DPO-1;DOP-1 (Diphenyl phosphine oxide-1);(+)-Neomenthyl diphenylphosphine oxide;inhibit,DPO1,Inhibitor,DPO 1,Potassium Channel,DPO-1,KcsA;(1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide;Phosphine oxide, [(1S,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl-;[1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide
CBNumber:
CB3850927
Molecular Formula:
C22H29OP
Molecular Weight:
340.44
MDL Number:
MFCD09038567
MOL File:
43077-30-1.mol
Last updated:2023-09-04 15:51:00

DPO-1 Properties

storage temp. Store at +4°C
solubility DMSO: soluble2mg/mL, clear (warmed)
form needles
color white
FDA UNII H9LQP293GK

SAFETY

Risk and Safety Statements

WGK Germany  3

DPO-1 price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D7443 DPO-1 needles, >97% (NMR) 43077-30-1 25mg $853 2023-06-20 Buy
Cayman Chemical 29688 DPO-1 43077-30-1 1mg $38 2024-03-01 Buy
Cayman Chemical 29688 DPO-1 43077-30-1 10mg $227 2024-03-01 Buy
Cayman Chemical 29688 DPO-1 43077-30-1 5mg $142 2024-03-01 Buy
Tocris 2533 DPO-1 ≥99%(HPLC) 43077-30-1 10 $173 2021-12-16 Buy
Product number Packaging Price Buy
D7443 25mg $853 Buy
29688 1mg $38 Buy
29688 10mg $227 Buy
29688 5mg $142 Buy
2533 10 $173 Buy

DPO-1 Chemical Properties,Uses,Production

Definition

ChEBI: [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene is a monoterpenoid.

Biological Activity

Blocker of I Kur ultrarapid delayed rectifier potassium current and K V 1.5 channels (IC 50 = 0.31 μ M for rK V 1.5). Displays selectivity for inhibition of I Kur over I to (8-fold), I K1 , I Kr and I Ks (20-fold) in native myocytes and selectivity for rat recombinant K V 1.5 over K V 3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.

storage

Store at +4°C

1079-66-9
43077-29-8
43077-30-1
Synthesis of DPO-1 from Chlorodiphenylphosphine

DPO-1 Preparation Products And Raw materials

Raw materials

Preparation Products

DPO-1 Suppliers

Global( 40)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4647 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4121 55
Shanghai Chiral bio-compound co., Ltd. 021-5068 3667/17749785980/1029026415; 17749785980 1029026415@qq.com China 2790 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Suzhou Nuobeike Biological Technology Co., Ltd. 13962527677 1551481742@qq.com China 248 58

DPO-1 Spectrum

DPO-1 [1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide (+)-Neomenthyl diphenylphosphine oxide (1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide Phosphine oxide, [(1S,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl- DOP-1 (Diphenyl phosphine oxide-1) inhibit,DPO1,Inhibitor,DPO 1,Potassium Channel,DPO-1,KcsA 43077-30-1 C22H29OP