ChemicalBook >> CAS DataBase List >>2,4-Lutidine

2,4-Lutidine

CAS No.
108-47-4
Chemical Name:
2,4-Lutidine
Synonyms
LUTIDINE;2,4-DIMETHYLPYRIDINE;24L;2,4-Lutidene;2,4-LUTIDINE;2,4-Lutidine>2,4-Lutidine 99%;2,4-LUTIDINE 98+%;2,4-dimethyl-pyridin;α,γ-dimethylpyridine
CBNumber:
CB3852754
Molecular Formula:
C7H9N
Molecular Weight:
107.15
MDL Number:
MFCD00006337
MOL File:
108-47-4.mol
MSDS File:
SDS
Last updated:2023-11-28 16:31:44

2,4-Lutidine Properties

Melting point -60 °C (lit.)
Boiling point 159 °C (lit.)
Density 0.927 g/mL at 25 °C (lit.)
vapor pressure 3.28hPa at 25℃
FEMA 4389 | 2,4-DIMETHYLPYRIDINE
refractive index n20/D 1.499(lit.)
Flash point 99 °F
storage temp. Flammables area
solubility 350g/l
pka 6.99(at 25℃)
form Liquid
color Colorless to Light yellow to Light orange
Odor at 0.01 % in dipropylene glycol. smoky phenolic
Odor Type smoky
Water Solubility 15 g/100 mL (20 ºC)
Sensitive Hygroscopic
JECFA Number 2151
BRN 1506
Dielectric constant 9.5999999999999996
InChIKey JYYNAJVZFGKDEQ-UHFFFAOYSA-N
LogP 1.9
CAS DataBase Reference 108-47-4(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 2,4-DIMETHYLPYRIDINE
EWG's Food Scores 1
FDA UNII 83903UJ0WW
NIST Chemistry Reference Pyridine, 2,4-dimethyl-(108-47-4)
EPA Substance Registry System 2,4-Dimethylpyridine (108-47-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06
Signal word  Danger
Hazard statements  H226-H301+H311+H331-H315-H319-H335
Precautionary statements  P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338
Hazard Codes  T,F,Xi
Risk Statements  10-23/24/25-36/37/38-25-20/21-20/21/22
Safety Statements  16-26-36/37/39-45
RIDADR  UN 1992 3/PG 3
WGK Germany  3
RTECS  OK9400000
8
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29333999
NFPA 704
2
3 1

2,4-Lutidine price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L3609 2,4-Lutidine 99% 108-47-4 5ml $19.98 2024-03-01 Buy
Sigma-Aldrich 68223 2,4-Lutidine analytical standard 108-47-4 1ml $67.2 2022-05-15 Buy
TCI Chemical L0085 2,4-Lutidine >98.0%(GC) 108-47-4 25mL $30 2024-03-01 Buy
TCI Chemical L0085 2,4-Lutidine >98.0%(GC) 108-47-4 500mL $204 2024-03-01 Buy
Alfa Aesar B22913 2,4-Lutidine, 98+% 108-47-4 25g $33.65 2024-03-01 Buy
Product number Packaging Price Buy
L3609 5ml $19.98 Buy
68223 1ml $67.2 Buy
L0085 25mL $30 Buy
L0085 500mL $204 Buy
B22913 25g $33.65 Buy

2,4-Lutidine Chemical Properties,Uses,Production

Chemical Properties

Colorless to pale-yellow clear liquid.

Chemical Properties

Clear pale yellow liquid, discoloring over time

Uses

2,4-Lutidine, can be used as a building block in the synthesis of various chemical compounds. It is also used tobacco and aroma component.

Definition

ChEBI: 2,4-Dimethylpyridine is a member of methylpyridines.

Aroma threshold values

High strength odor, recommend smelling in a 0.01% solution or less.

Purification Methods

Dry it with Linde type 5A molecular sieves, BaO or sodium, and fractionally distil it. The distillate (200g) is heated with *benzene (500mL) and conc HCl (150mL) in a Dean and Stark apparatus on a water bath until water no longer separates, and the temperature just below the liquid reaches 80o. When cold, the supernatant *benzene is decanted, and the 2,4-lutidine hydrochloride, after washing with a little *benzene, is dissolved in water (350mL). After removing any *benzene by steam distillation, an aqueous solution of NaOH (80g) is added, and the free lutidine is steam distilled. It is isolated by saturating the distillate with solid NaOH and distilling it through a short column. The precipitation cycle is repeated, then the final distillate is partly frozen in an apparatus at -67.8-68.5o (cooled by acetone/CO2). The crystals are collected, then melted and distilled. [Kyte et al. J Chem Soc 4454 1960.] Alternative purifications are via the picrate m 183-184o (from H2O). [Clarke & Rothwell J Chem Soc 1885 1960], or the hydrobromide [Warnhoff J Org Chem 27 4587 1962]. The latter is precipitated from a solution of lutidine in *benzene by passing dry HBr gas: the salt is recrystallised from CHCl3/methyl ethyl ketone, then decomposed with NaOH, and the free base is extracted into Et2O, dried, evaporated and the residue is distilled. [Beilstein 20 H 244, 20 II 180, 20 III/IV 2718, 20/6 V 19.]

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View Lastest Price from 2,4-Lutidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Lutidine pictures 2023-08-14 2,4-Lutidine
108-47-4
US $100.00-50.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
2,4-Lutidine pictures 2023-07-27 2,4-Lutidine
108-47-4
US $1.50 / g 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
2,4-Lutidine pictures 2023-07-05 2,4-Lutidine
108-47-4
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
  • 2,4-Lutidine pictures
  • 2,4-Lutidine
    108-47-4
  • US $100.00-50.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co,.LTD
  • 2,4-Lutidine pictures
  • 2,4-Lutidine
    108-47-4
  • US $1.50 / g
  • 99.0% Min
  • Shaanxi Didu New Materials Co. Ltd
  • 2,4-Lutidine pictures
  • 2,4-Lutidine
    108-47-4
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
2,4-LUTIDINE 98+% 2,4-DIMETHYLPYRIDINE(2,4-LUTIDINE) Dimethylpyridine, 2,4-: (2,4-Lutidine) 2,4-Lutidine, 98+% 500ML 2,4-DIMETHYLPYRIDINE FOR SYNTHESIS 2,4-Lutidine 99% alpha,gamma-Dimethylpyridine Pyridine,2,4-dimethyl- α,γ-dimethylpyridine 2,4-dimethyl-pyridin 2,4-Lutidene 24L 2,4-LUTIDINE 4,6-DIMETHYLPYRIDINE 2,4-Lutidine> 2,4-Lutidine ISO 9001:2015 REACH 2,4-DIMETHYLPYRIDINE LUTIDINE 108-47-4 558-17-4 198-47-4 108-47-8 Reagents for Oligosaccharide Synthesis C7 and C8 Building Blocks Pyridines Heterocyclic Building Blocks Building Blocks C7 Chemical Synthesis Heterocyclic Building Blocks Pyridines Biochemistry Reagents for Oligosaccharide Synthesis Heterocyclic Compounds Organics