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1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine structure

CAS No.: 120014-07-5

Chemical Name:: 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine

Synonyms: Donepezil-013;Donepezil-013-Z;Dehydro Donepezi;Dehydro Donepezil;Donepezil USP RC A;Donepezil Impurity O;Donepezil Impurity 17;Donepezil related compound;1-Benzyl-4-(5,6-dimethoxy-1-ox;2-[(1-Benzylpiperidin-4-yl)methylen

CBNumber:: CB3854945

Molecular Formula:: C24H27NO3

Molecular Weight:: 377.48

MDL Number:: MFCD08693144

MOL File:: 120014-07-5.mol

MSDS File:: SDS

Last updated:2022-12-30 16:20:48

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1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine Properties

Melting point	176-178°C
Boiling point	542.8±50.0 °C(Predicted)
Density	1.209±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	8.03±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
HS Code	2933399990

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	J11663	Donepezilrelatedcompound(E/Zmixture)	120014-07-5	100mg	$49	2021-12-16	Buy
Oakwood	036506	1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine 97%	120014-07-5	1g	$55	2021-12-16	Buy
Biosynth Carbosynth	IB18353	1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine	120014-07-5	100mg	$60	2021-12-16	Buy
Biosynth Carbosynth	IB18353	1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine	120014-07-5	250mg	$100	2021-12-16	Buy
Apolloscientific	OR61173	2-[(1-Benzylpiperidin-4-yl)methylidene]-2,3-dihydro-5,6-dimethoxy-1H-inden-1-one 97%	120014-07-5	5g	$137	2021-12-16	Buy

Product number	Packaging	Price	Buy
J11663	100mg	$49	Buy
036506	1g	$55	Buy
IB18353	100mg	$60	Buy
IB18353	250mg	$100	Buy
OR61173	5g	$137	Buy

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine Chemical Properties,Uses,Production

Synthesis

A solution of 5,6-dimethoxy-indanone (19 g, 0.10 mol) in methanol (8 mL) is stirred under inert atmosphere at room temperature. Slowly add NaOH flakes (12.8 g, 0.32 mol) followed by N-benzyl-piperidine-4-carboxaldehyde (20.2 g, 0.10 mol) to the reaction mixture. The mixture was stirred at room temperature for 3 h and progress of the reaction was monitored by TLC (hexane:ethyl acetate; 1:1). Once the reaction is complete, the solid formed was filtered, washed with 5 % acetic acid and then with methanol and dried. The obtained solid (34 g) was taken into a round bottom flask and refluxed with DMF (50 mL). Gradually cooled to room temperature and stirred for 2 h, filtered the solid formed, wash with chilled methanol to afford a pale yellow crystalline solid 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine (32.0 g, 84 %); m.p.: 175-177 °C.

Uses

An impurity of Donepezil; an intermediate as an anti-Alzheimer agent.

Uses

An impurity of Donepezil (D531750); an intermediate as an anti-Alzheimer's agent.

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine Suppliers

Global( 126)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10828	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
PT CHEM GROUP LIMITED	+86-85511178 +86-85511178	peter68@ptchemgroup.com	China	35453	58

Supplier	Advantage
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
sgtlifesciences pvt ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
PT CHEM GROUP LIMITED	58

View Lastest Price from 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-03	1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine 120014-07-5	US $1.00 / KG	1KG	99%	10000KGS	Career Henan Chemical Co

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine
120014-07-5
US $1.00 / KG
99%
Career Henan Chemical Co

120014-07-5(1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine)Related Search:

2,6-Dimethoxybenzaldehyde Dimethyldimethoxysilane Diphenyldimethoxysilane Benzyl benzoate Dimethoxymethane

Benzyl isocyanate Benzyl chloride N,N-Dimethylbenzylamine Haloperidol 1,1-Dimethoxyethane

Benzyl nicotinate Benzyl alcohol Benzyltriethylammonium chloride 5,6-Dimethoxy-1-indanone Donepezil

XWAIAVWHZJNZQQ-RPXFAUAJSA-N 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one 5-O-Desmethyl Donepezil

1of4

1-Benzyl-4-(5,6-dimethoxy-1-ox 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2- 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine 2-(1-Benzylpiperidin-4-ylmethylidene)-5,6-dimethoxyindan-1-one 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-1H-inden-1-one Dehydro Donepezil (Donepezil Impurity) 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydroinden-1-one 1-Benzyl-4-[(5,6-diMethoxy-1-oxoindan-2-ylidene)Methyl]piperidine (Donepezil IMpurity) 1-Benzyl-4-(5,6-diMethoxy-1-oxoindan-2-ylindeneMet Dehydro Donepezi Donepezil USP RC A 1-Benzyl-4-[(1,3-dihydro-5,6-dimethoxy-1-oxo-2H-inden-2-ylidene)methyl]piperidine 2-[(1-Benzylpiperidin-4-yl)methylidene]-2,3-dihydro-5,6-dimethoxy-1H-inden-1-one Donepezil related coMpound (E/Z Mixture) 1H-Inden-1-one, 2,3-dihydro- 5,6-diMethoxy-2-[[1-( phenylMethyl)-4-piperidinyl] Methylene]- (E)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one Dehydro Donepezil 1-benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine 2-[(1-benzyl-4-piperidyl)methyleen]-5,6-dimethoxyindan-1-on 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one 2-[(1-Benzylpiperidin-4-yl)methylidene]-2,3-dihydro-5,6-dimethoxy-1H-inden-1-one 97% Donepezil-013 Donepezil impurity 16/1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine Donepezil related compound Donepezil Impurity O Donepezil-013-Z Donepezil Impurity 17 2-[(1-Benzylpiperidin-4-yl)methylen 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine DISCONTINUED. Please see D229775 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperi... Donepezil Dehydro Impurity (E/Z mixture) (E)-1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine 120014-07-5 C24H27NO3 Aromatics Heterocycles Intermediates Intermediates & Fine Chemicals Pharmaceuticals