ChemicalBook >> CAS DataBase List >>tert-Butyl rosuvastatin
tert-Butyl rosuvastatin
- CAS No.
- 355806-00-7
- Chemical Name:
- tert-Butyl rosuvastatin
- Synonyms
- Rosuvastatin tert-butyl ester;Rosuvastatin t-Butyl Ester;tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate;(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester;ZD-8;R1.5;tert-Butyl rosuvasta;ert-Butylrosuvastatin;dihydroxyhept-6-enoate;Rosuvastatin tert-butyl
- CBNumber:
- CB3855018
- Molecular Formula:
- C26H36FN3O6S
- Molecular Weight:
- 537.64
- MDL Number:
- MFCD08460212
- MOL File:
- 355806-00-7.mol
Last updated:2023-07-11 16:12:39
| Melting point | 136-138oC |
|---|---|
| Boiling point | 704.2±70.0 °C(Predicted) |
| Density | 1.259 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated) |
| pka | 13.38±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| CAS DataBase Reference | 355806-00-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
tert-Butyl rosuvastatin price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | R700540 | Rosuvastatintert-ButylEster | 355806-00-7 | 100mg | $175 | 2021-12-16 | Buy |
| Usbiological | 290783 | Tert-Butyl Rosuvastatin | 355806-00-7 | 50g | $545 | 2021-12-16 | Buy |
| Matrix Scientific | 093655 | (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester 95+% | 355806-00-7 | 5g | $756 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 52968 | Rosuvastatintert-ButylEster | 355806-00-7 | 1g | $2120 | 2021-12-16 | Buy |
| Matrix Scientific | 093655 | (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester 95+% | 355806-00-7 | 1g | $284 | 2021-12-16 | Buy |
tert-Butyl rosuvastatin Chemical Properties,Uses,Production
Uses
Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.
Uses
tert-Butyl Rosuvastatin is an impurity of Rosuvastatin (287714-41-4 #CAS), which is a HMG-?CoA reductase inhibitor. In combination of pemafibrate or a salt, it can function as cardiovascular disease medication.
Synthesis of tert-Butyl rosuvastatin from tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
tert-Butyl rosuvastatin Preparation Products And Raw materials
Raw materials
1,3-Dioxane-4-acetic acid, 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2-phenyl-, 1,1-dimethylethyl ester, (4R,6S)-
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
Preparation Products
Global( 199)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 | sales@ichemie.com | China | 985 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Chenghui-Shuangda Chemical Co.,Ltd | +86-531-58897082 | ericqiao@jnchsd.com | CHINA | 158 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
View Lastest Price from tert-Butyl rosuvastatin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-11-01 | tert-Butyl rosuvastatin
355806-00-7
|
US $0.00-0.00 / KG | 1KG | 98% | 200 | Hangzhou ICH Biofarm Co., Ltd | |
 |
2022-02-25 | tert-Butyl rosuvastatin
355806-00-7
|
US $5.60 / KG | 1KG | 99% | 1000tons | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2022-02-25 | tert-Butyl rosuvastatin
355806-00-7
|
US $19.00 / KG | 1KG | 99% | 20kg | Hong Kong Tiansheng New Material Trading Co., Ltd |
-
- tert-Butyl rosuvastatin
355806-00-7
- US $0.00-0.00 / KG
- 98%
- Hangzhou ICH Biofarm Co., Ltd
-
- tert-Butyl rosuvastatin
355806-00-7
- US $5.60 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- tert-Butyl rosuvastatin
355806-00-7
- US $19.00 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
355806-00-7(tert-Butyl rosuvastatin)Related Search:
(+)-(3R, 5S)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHANESULFONYLAMINO)PYRIMIDIN-5-YL]-(3, 5)-DIHYDROXY-6(E)-HEPTENOATE
Rosuvastatin intermediate R-3
tert-Butyl(+)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesul
fonylamino)pyrimidin-5-yl]-3,5-Dihydroxy-6(E)-Heptenoate
ZD-8
Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N- methylsulfonylamino)pyrimidine-5-yl] -(3R,5S) -dihydroxy -(E)-6-Heptena
Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R,5S)-dihydroxy
(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)]-2-[Methyl(Methylsulfonyl)aMino-5-pyriMidinyl]-3,5-dihydroxy-6-heptenoicacidtert-butylester
T-BUTYL 7-[4-(4-FLUOROPHENYL)-6-ISO-PROPYL-2-(N-METHYL-N-METHYLSULFONYLAMINO)PYRIMIDIN-5-YL] -(3R,5S)-DIHYDROXY-(E)-6-HEPTENATE
tert-Butyl rosuvasta
Rosuvastatin calciuM interMediate R-3
(3R,5S,6E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(METHANESULFONYL) METHYL AMINO]PYRIMIDIN-5-YL
Rosuvastatin Acid t-Butyl Ester
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,
tert-Butyl Rosuvastatin (Rosuvastatin IMpurity)
Rosuvastatin tert-butyl
(+)-(3r, 5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5-Dihydroxy-6(E)-Heptenate (R1.5 Or T-Butyl-Rosuvastatin)
R-1.5: (+)-(3R, 5S), TERT-BUTYL 7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHYLSULPHONYLAMINO)-PYRIMIDINE-5-YL]-3, 5-DIHYDROXY-6(E)-HEPTENATE
(E) - (3R,5S)-7-{4-(4-FLUOROPHENYL)-6-ISOPROPYL-2{METHYL SULPHONYLAMINO)] PYRIMIDIN-5-YL}-3,5-DIHYDROXYHEPTEN6-6 OICACID
tert-butyl rosuvastatin
dihydroxyhept-6-enoate
7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid t-butyl ester
tert-butyl (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-
methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-
6-enoate
Rosuvatatin Impurity 22
Rosuvastatin Impurity 77
Rosuvastatin calcium-001
Rosuvastatin calcium-001-3R5S
Rosuvastatin Impurity 20
(tert-Butyl Rosuvastatin)
Rosuvastatin Impurity 7/Rosuvastatin tert-Butyl Ester/(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
Rosuvastatin calcium-11
R1.5
6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-
ert-Butylrosuvastatin
tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-
[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-
dihydroxyhept-6-enoate(R2)
tert-Butyl rosuvastatin,(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid,Methyl ester
(+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5-Dihydroxy-6(E)-Heptenate (R1.5 Or T-Butyl-Rosuvastatin)
(+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-...
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate
Rosuvastatin tert-butyl ester
Rosuvastatin t-Butyl Ester
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
Rivastatin tert-butyl ester
Rosuvastatin calcium impurity 10
Rosuvastatin EP Impurity 10
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2 [(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5 dihydroxyhept -6-enoic acid tert-butyl ester or (Tert Butyl Rosuvastatin)
tert-Butyl Rosuvastatir
355806-00-7
C26H36FN3O6S
Rosuvastatin intermediates
Rosuvastatin Calcium and its intermediates