Propiverine hydrochloride
- CAS No.
- 54556-98-8
- Chemical Name:
- Propiverine hydrochloride
- Synonyms
- Bup-4;Urecure;Noraguard;Nsc172140;Pollarine;mictonorm;Uronaverine;Mictonetten;PROPIVERINE HCL;Yansuan Bingpaiweilin
- CBNumber:
- CB3855472
- Molecular Formula:
- C23H30ClNO3
- Molecular Weight:
- 403.94
- MDL Number:
- MFCD01672343
- MOL File:
- 54556-98-8.mol
- MSDS File:
- SDS
| Melting point | 224-226°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| CAS DataBase Reference | 54556-98-8(CAS DataBase Reference) |
| FDA UNII | DC4GZD10H3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H335 | |||||||||
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AH3297000 | |||||||||
| Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 36, 36, 22, 25 i.v.; 223, 283, 1632, 1411 s.c.; 410, 323, 1000, 1092 orally (Yamashita) | |||||||||
| NFPA 704 |
|
Propiverine hydrochloride price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0602 | Propiverine hydrochloride ≥98% (HPLC) | 54556-98-8 | 5mg | $37.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0602 | Propiverine hydrochloride ≥98% (HPLC) | 54556-98-8 | 100mg | $193 | 2024-03-01 | Buy |
| TRC | P828000 | Propiverine hydrochloride | 54556-98-8 | 250mg | $225 | 2021-12-16 | Buy |
| TRC | P828000 | Propiverine hydrochloride | 54556-98-8 | 100mg | $110 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 13193 | PropiverineHCl | 54556-98-8 | 100mg | $845 | 2021-12-16 | Buy |
Propiverine hydrochloride Chemical Properties,Uses,Production
Description
Propiverine hydrochloride is a new urological agent developed for pollakuria and aconuresis. It appears to exhibit anticholinergic properties and in animal experiments inhibited KCl induced contractions in the bladder and ileum.
Chemical Properties
Off-White Solid
Originator
Apogepha (Germany)
Uses
Propiverine is used in treatment of urinary incontinence. Propiverine is an anticholinergic.
Definition
ChEBI: Propiverine hydrochloride is a diarylmethane.
brand name
Mictonorm; Mictonetten
General Description
Propiverine hydrochloride drug is a tertiary amine with spasmolytic and analgesic properties. This drug exerts neurotropic and musculotropic effects on the urinary bladder and smooth muscles. Propiverine hydrochloride has a half-life of 20 hours.
Biochem/physiol Actions
Propiverine is an antimuscarinic drug used for the treatment of overactive blaqdder and urinary incontinence. Propiverine and/or its metabolites also have calcium channel blocking properties in addition to antimuscarinic activity, which may contribute to the clinical activity.
Clinical Use
Treatment of urinary frequency, urgency and
incontinence
Neurogenic bladder instability
Drug interactions
Potentially hazardous interactions with other drugs
Anti-arrhythmics: increased risk of antimuscarinic
side effects with disopyramide.
Metabolism
Propiverine is extensively metabolised by intestinal and
hepatic enzymes. Four metabolites were identified in
urine; two of them are pharmacologically active and may
contribute to the therapeutic efficacy.
Propiverine and its metabolites are excreted in the urine,
bile and faeces.
Propiverine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1320 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
View Lastest Price from Propiverine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-25 | Propiverine hydrochloride
54556-98-8
|
US $15.00 / kg | 1kg | 99.912% | 10ton | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2023-07-04 | Propiverine hydrochloride
54556-98-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-06-15 | Propiverine hydrochloride
54556-98-8
|
US $1142.00 / Kg/Bag | 100g | 99% | 100kg | Baoji Guokang Bio-Technology Co., Ltd. |
-
- Propiverine hydrochloride
54556-98-8
- US $15.00 / kg
- 99.912%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Propiverine hydrochloride
54556-98-8
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Propiverine hydrochloride
54556-98-8
- US $1142.00 / Kg/Bag
- 99%
- Baoji Guokang Bio-Technology Co., Ltd.