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4-O-(Carboxymethyl)rifamycin

4-O-(Carboxymethyl)rifamycin structure

CAS No.: 13929-35-6

Chemical Name:: 4-O-(Carboxymethyl)rifamycin

Synonyms: C01848;Nacimycin;Nancimycin;Rifomycin B;NCI-145-604;Rifamycin B CRS;Rifamycin impurity A;Rifaximin EP Impurity B;Rifamycin EP Impurity A;Rifaximin impurity B (EP)

CBNumber:: CB3913884

Molecular Formula:: C39H49NO14

Molecular Weight:: 755.8

MDL Number:

MOL File:: 13929-35-6.mol

Modify Date:2022-12-21 16:56:50

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4-O-(Carboxymethyl)rifamycin Properties

Melting point	300° (dec 160-164°)
alpha	D20 -11° (methanol)
Boiling point	730.16°C (rough estimate)
Density	1.2421 (rough estimate)
refractive index	1.5350 (estimate)
form	neat
pka	2.69±0.10(Predicted)
BRN	604953
FDA UNII	8DDB535DJI

SAFETY

Risk and Safety Statements

Toxicity	LD50 in mice (mg/kg): 2040 i.v., >3000 i.p., s.c., and orally (Sensi, 1964)

4-O-(Carboxymethyl)rifamycin price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	R0900000	Rifamycin B European Pharmacopoeia (EP) Reference Standard	13929-35-6	r0900000	$218	2023-01-07	Buy
TRC	R508170	Rifamycin B	13929-35-6	50mg	$160	2021-12-16	Buy
TRC	R508170	Rifamycin B	13929-35-6	500mg	$1295	2021-12-16	Buy
American Custom Chemicals Corporation	API0009903	RIFAMYCIN B 95.00%	13929-35-6	500MG	$1871.1	2021-12-16	Buy
American Custom Chemicals Corporation	API0009903	RIFAMYCIN B 95.00%	13929-35-6	50MG	$315	2021-12-16	Buy

Product number	Packaging	Price	Buy
R0900000	r0900000	$218	Buy
R508170	50mg	$160	Buy
R508170	500mg	$1295	Buy
API0009903	500MG	$1871.1	Buy
API0009903	50MG	$315	Buy

4-O-(Carboxymethyl)rifamycin Chemical Properties,Uses,Production

Uses

Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin (R508200) derivative as antibacterial agent.

Uses

A Rifamycin (R508200) derivative as antibacterial agent.

Purification Methods

Rifamycin B forms yellow needles from *C6H6. Its solubilities are: H2O (0,027%), MeOH (2.62%) and EtOH (0.44%). It has UV max at 223, 304 and 245nm (A 1cm 555, 275 and 220). [Oppolzer & Prelog Helv Chim Acta 56 2287 1973, Oppolzer et al. Experientia 20 336 1964, X-ray: Brufani et al. Experientia 20 339 1964.]

4-O-(Carboxymethyl)rifamycin Preparation Products And Raw materials

Raw materials

Preparation Products

4-O-(Carboxymethyl)rifamycin Suppliers

Global( 35)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21975	55
Guangzhou PI PI Biotech Inc	+86-020-81716320 +86-18371201331	Sales@pipitech.com	China	3635	55
Hubei Jusheng Technology Co.,Ltd.	86-18871470254	linda@hubeijusheng.com	CHINA	28185	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
HENAN BON INDUSTRIAL CO.,LTD	0371-55170695	info@hnbon.com	CHINA	26700	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15525	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19650	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Hangzhou Yuhao Chemical Technology Co., Ltd	0571-82693216	info@yuhaochemical.com	China	9394	52

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Guangzhou PI PI Biotech Inc	55
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
HENAN BON INDUSTRIAL CO.,LTD	58
AFINE CHEMICALS LIMITED	58
BOC Sciences	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
Hangzhou Yuhao Chemical Technology Co., Ltd	52

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Rifamycin impurity A Rifaximin EP Impurity B Rifamycin, 4-O-(carboxymethyl)- 4-O-(Carboxymethyl)rifamycin Nacimycin Nancimycin NCI-145-604 Rifomycin B C01848 Rifaximin impurity B (EP) Rifaximin Impurity 2 (Rifaximin EP Impurity B) Rifamycin EP Impurity A Rifaximin EP Impurity B (Rifamycin B) Rifamycin B CRS Rifamycin Impurity 1(Rifamycin EP Impurity A)（Rifamycin B) 13929-35-6 C39H49NO14 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals