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9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole

CAS No.
10371-86-5
Chemical Name:
9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
Synonyms
ICIG-772;NSC-69187;9-Methoxyellipticin;9-methoxyellipticine;9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole;6H-Pyrido[4,3-b]carbazole, 9-methoxy-5,11-dimethyl-
CBNumber:
CB3918854
Molecular Formula:
C18H16N2O
Molecular Weight:
276.33
MDL Number:
MFCD00049339
MOL File:
10371-86-5.mol
Last updated:2023-06-08 09:03:02

9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole Properties

Melting point 286.5°C (rough estimate)
Boiling point 419.24°C (rough estimate)
Density 1.1318 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. -20°C
solubility DMSO: soluble
form A solid
pka 16.29±0.40(Predicted)
FDA UNII U0924292N9

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
NFPA 704
0
2 0

9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole Chemical Properties,Uses,Production

Description

An Ochrosia alkaloid present in O. oppositifolia and O. sandwicensis Gray, it occurs mainly in the bark of these species. It forms light yellow crystals and gives an ultraviolet spectrum in EtOH with absorption maxima at 242, 275, 290 and 335 mil. It may be characterized as the hydrochloride which has m.p. 288- 290°C following a change in crystal form at 255-265°C, or as the picrate, m.p. 273-5°C. The structure has been elucidated from the mass spectrum fragmentation pattern.

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 7106, 2007 DOI: 10.1021/jo070774z

References

Buzas, Osowiecki, Schindler., Cornpt. Rend., 247, 1390 (1958)
Goodwin, Smith, Horning.,!. Arner. Chern. Soc., 81,1903 (1959)
Mass spectrum:
Loder., Austral. J. Chern., 19, 1947 (1966)
Synthesis:
Dalton et aI., Austral. J. Chern., 20, 2715 (1967)

9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole Preparation Products And Raw materials

Raw materials

Preparation Products

9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole Suppliers

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9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole 9-methoxyellipticine 9-Methoxyellipticin ICIG-772 NSC-69187 6H-Pyrido[4,3-b]carbazole, 9-methoxy-5,11-dimethyl- 10371-86-5