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sulforidazine

CAS No.
14759-06-9
Chemical Name:
sulforidazine
Synonyms
sulforidazine;Thioridazine 2-Sulfone;Thioridazine EP Impurity E;Thioridazine Impurity 5 (Thioridazine EP Impurity E);10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-;10-[2-[(2RS)-1-Methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine;10-[2-[(2RS)-1-methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine (sulforidazine);10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylsulfonyl)-10H-phenothiazine (Thioridazine Impurity)
CBNumber:
CB3920154
Molecular Formula:
C21H26N2O2S2
Molecular Weight:
402.57
MDL Number:
MOL File:
14759-06-9.mol
Last updated:2023-05-04 17:34:33

sulforidazine Properties

Melting point 121-123°
Boiling point 589.1±50.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
storage temp. Refrigerator, Under Inert Atmosphere
solubility Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 9.83±0.10(Predicted)
color Off-White to Dark Yellow
FDA UNII B7599I244X

sulforidazine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T368810 Thioridazine2-Sulfone 14759-06-9 50mg $1455 2021-12-16 Buy
American Custom Chemicals Corporation API0012528 SULFORIDAZINE 95.00% 14759-06-9 5MG $345.4 2021-12-16 Buy
aablocks AA001EXB 10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)- 14759-06-9 5mg $315 2021-12-16 Buy
aablocks AA001EXB 10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)- 14759-06-9 50mg $1470 2021-12-16 Buy
Product number Packaging Price Buy
T368810 50mg $1455 Buy
API0012528 5MG $345.4 Buy
AA001EXB 5mg $315 Buy
AA001EXB 50mg $1470 Buy

sulforidazine Chemical Properties,Uses,Production

Chemical Properties

Thick Yellow Oil

Originator

Sulforidazine,ZYF Pharm Chemical

Uses

Thioridazine 2-Sulfone (Thioridazine EP Impurity E) is a major metabolite of Thioridazine (THD 2-SO2).

Definition

ChEBI: Sulforidazine is a member of phenothiazines.

Manufacturing Process

A mixture of 96.5 g 2-methylsulfonylphenothiazine, 50 g 2-(2-chloroethyl)-1- methylpiperidine, 62 g diethyl carbonate and 2 g sodium methylate was heated at 135°C for 1 hour and then at 180-190°C for 2.5 hours. The product was dissolved in benzene (500 ml) and the solution was extracted with 700 ml of 15% aqueous solution tartaric acid. The extract was washed with benzene. After addition of sodium carbonate solution to the extract was obtained a precipitate which was dissolved in benzene. This solution was washed with water and concentrated. 2-Methylsulfonyl-10-(2-(1-methyl-2- piperidyl)ethyl)phenothiazin was recrystallized from acetone, melting point 121-123°C.

Therapeutic Function

Neuroleptic

sulforidazine Preparation Products And Raw materials

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Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
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sulforidazine Thioridazine 2-Sulfone Thioridazine EP Impurity E Thioridazine Impurity 5 (Thioridazine EP Impurity E) 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)- 10-[2-[(2RS)-1-Methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine 10-[2-[(2RS)-1-methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine (sulforidazine) 10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylsulfonyl)-10H-phenothiazine (Thioridazine Impurity) 14759-06-9 Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Sulfur & Selenium Compounds