PipaMperone Dihydrochloride
- CAS No.
- 2448-68-2
- Chemical Name:
- PipaMperone Dihydrochloride
- Synonyms
- Nsc170981;carpiperone;fluoropipamide;Pipamperone 2HCl;Pipamperone DiHCl;Pipamperone hydrochloride;PIPAMPERONE DIHYDROCHLORIDE;floropipamide hydrochloride;Pipamperone dihydrochloride salt;R4050, 1μ-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4μ-bipiperidine]-4μ-carboxamide dihydrochloride
- CBNumber:
- CB3938249
- Molecular Formula:
- C21H30FN3O2.2ClH
- Molecular Weight:
- 0
- MDL Number:
- MFCD00242980
- MOL File:
- 2448-68-2.mol
- MSDS File:
- SDS
Last updated:2023-05-15 10:43:46
| Melting point | 203-218°C |
|---|---|
| storage temp. | Hygroscopic, Refrigerator, Under Inert Atmosphere |
| solubility | H2O: ~50mg/mL |
| form | powder |
| color | white |
| Stability | Hygroscopic |
| FDA UNII | IT085U64JB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 1 |
| RTECS | DW1060000 |
| Toxicity | mouse,LD50,intravenous,71mg/kg (71mg/kg),Drugs in Japan Vol. 6, Pg. 631, 1982. |
PipaMperone Dihydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P3246 | Pipamperone dihydrochloride ~99% (HPLC), powder | 2448-68-2 | 100mg | $260 | 2024-03-01 | Buy |
| TRC | P475200 | Pipamperone dihydrochloride | 2448-68-2 | 10mg | $145 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008335 | PIPAMPERONE DIHYDROCHLORIDE 95.00% | 2448-68-2 | 100MG | $716.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008335 | PIPAMPERONE DIHYDROCHLORIDE 95.00% | 2448-68-2 | 1G | $1686.3 | 2021-12-16 | Buy |
PipaMperone Dihydrochloride Chemical Properties,Uses,Production
Chemical Properties
Off-White to Pale Yellow Solid
Uses
Pipamperone dihydrochloride may be used:
- as an internal standard in liquid chromatography with coulometric detection
- as an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channel
- as an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis
Uses
Antipsychotic.
Definition
ChEBI: A hydrochloride resulting from the reaction of pipamperone with 2 mol eq. of hydrogen chloride. It is used as an antipsychotic.
Biochem/physiol Actions
Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.
PipaMperone Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
PipaMperone Dihydrochloride Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
Pipamperone hydrochloride
R4050, 1μ-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4μ-bipiperidine]-4μ-carboxamide dihydrochloride
Nsc170981
Pipamperone DiHCl
PIPAMPERONE DIHYDROCHLORIDE
Pipamperone dihydrochloride salt
carpiperone
floropipamide hydrochloride
fluoropipamide
Pipamperone 2HCl
2448-68-2
C21H30N3O2F2HCl
C21H32Cl2FN3O2
Amines
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals