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3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-

3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- structure

CAS No.: 2763260-30-4

Chemical Name:: 3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-

Synonyms: inhibit,NRX-1933,NRX1933,Inhibitor,NRX 1933;3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-

CBNumber:: CB410999510

Molecular Formula:: C14H9F3N6O2

Molecular Weight:: 350.26

MDL Number:

MOL File:: 2763260-30-4.mol

Last updated:2024-07-02 08:55:07

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3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- Properties

Density	1.617±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 83.33 mg/mL (237.91 mM; Need ultrasonic)
form	Solid
pka	4.17±0.10(Predicted)
color	White to off-white

3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- Chemical Properties,Uses,Production

Biological Activity

NRX-1933 is a β-catenin:β-TrCP interaction enhancer for the development of small molecule degraders.

References

[1]. Simonetta KR, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402.

3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32836	60
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	5586	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11976	58
https://hanhongsci.com/	021-54306202 18917919676	info@hanhongsci.com	China	29978	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Aladdin Scientific	58
DC Chemicals	58
Nanjing Tengyi Biotechnology Co., Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
https://hanhongsci.com/	58

3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-N-[3-(2H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)- inhibit,NRX-1933,NRX1933,Inhibitor,NRX 1933 2763260-30-4 C14H9F3N6O2