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MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE structure

CAS No.: 65144-34-5

Chemical Name:: MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

Synonyms: SPCK;HLE INHIBITOR;MEOSUC-AAPV-CMK;MEOSUC-APPV-CMK;ELASTASE INHIBITOR III;Elastase Inhibitor, SPCK;MEOSUC-ALA-ALA-PRO-VAL-CMK;N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.&;MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE;methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone

CBNumber:: CB4111744

Molecular Formula:: C22H35ClN4O7

Molecular Weight:: 502.99

MDL Number:: MFCD00077136

MOL File:: 65144-34-5.mol

Last updated:2023-04-23 13:52:06

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MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Properties

Melting point	159-161 °C
Boiling point	809.4±65.0 °C(Predicted)
Density	1.234±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	ethanol: 50 mg/mL, clear, colorless
form	Solid
pka	13.05±0.20(Predicted)
Sensitive	Moisture Sensitive
BRN	6167019

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3
F	10

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M0398	N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone elastase inhibitor	65144-34-5	5mg	$170	2024-03-01	Buy
Sigma-Aldrich	M0398	N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone elastase inhibitor	65144-34-5	10mg	$291	2024-03-01	Buy
Sigma-Aldrich	324745	Elastase Inhibitor III The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.		5MG	$238	2023-06-20	Buy
Alfa Aesar	J65894	Elastase Inhibitor III	65144-34-5	5mg	$123	2021-12-16	Buy
Sigma-Aldrich	M0398	N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone elastase inhibitor	65144-34-5	25mg	$549	2024-03-01	Buy

Product number	Packaging	Price	Buy
M0398	5mg	$170	Buy
M0398	10mg	$291	Buy
324745	5MG	$238	Buy
J65894	5mg	$123	Buy
M0398	25mg	$549	Buy

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Chemical Properties,Uses,Production

Uses

A potent irreversible inhibitor of human leukocyte elastase

Definition

ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.

General Description

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

Biochem/physiol Actions

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Suppliers

Global( 69)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing TGpeptide	+86-13347807150 +86-13347807150	support@tgpeptide.com	China	3279	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696;	info@hanhongsci.com	China	42982	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
ApexBio Technology LLC	+1-832-696-8203	info@apexbt.com	United States	477	60
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

Supplier	Advantage
Nanjing TGpeptide	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
GL Biochem (Shanghai) Ltd	64
VDM Biochemicals	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
AdooQ BioScience, LLC	58
ApexBio Technology LLC	60
Sigma-Aldrich	80

65144-34-5(MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE)Related Search:

Elastase 2-AMINO-1-PYRROLIDIN-1-YL-ETHANONE HCL N,N-DIETHYL-2-(METHYLAMINO)ACETAMIDE HYDROCHLORIDE N-ME-GLY-NME2 1-ACETAMIDO-ACETONE

MEOSUC-ALA-ALA-PRO-ALA-CHLOROMETHYLKETONE H-ALA-PRO-NH2 HCL Methyl 4-aminobutyrate hydrochloride H-ALA-ALA-ALA-NH2 HCL 2-AMINO-N,N-DIETHYL-ACETAMIDE HCL

N-(1-methyl-2-oxopropyl)acetamide ALA-ALA-PRO-VAL-CMK H-PRO-NHET HCL 2-METHYLAMINO-1-PYRROLIDIN-1-YL-ETHANONE X HCL >98% MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

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N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE MEOSUC-APPV-CMK MEOSUC-AAPV-CMK MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE MEOSUC-ALA-ALA-PRO-VAL-CMK ELASTASE INHIBITOR III HLE INHIBITOR N-(methoxysuccinyl)-L-ala-L-ala-L-prol.-L-val-chlorome.ket. N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL*CHLORO METHYL KETO N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.& N(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine CMK SPCK Elastase Inhibitor, SPCK methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-(1-methylethyl)-2-oxopropyl]- 65144-34-5 C22H35ClN4O7 C22H35N4O7Cl Biochemicals and Reagents BioChemical Cell Biology Cell Signaling and Neuroscience Metalloproteinase Inhibitors Cytoskeleton and Extracellular Matrix Enzyme Inhibitors Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Extracellular Matrix Substrate Analogs ProteaseInhibitors