Ipamorelin
- CAS No.
- 170851-70-4
- Chemical Name:
- Ipamorelin
- Synonyms
- IpaMorelin Acetate;Aib-His-D-2-Nal-D-Phe-Lys-NH2;Ipamoreli;IpoMarelin;IPAMORELIN;lpamorelin;NNC-26-0161;IPAMOREILIN;Iparmorelin;IPAMORELIN(5MG)
- CBNumber:
- CB41117534
- Molecular Formula:
- C38H49N9O5
- Molecular Weight:
- 711.85
- MDL Number:
- MFCD02179658
- MOL File:
- 170851-70-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ipamorelin acetate ≥98% | SML1322 | 10MG | $92.5 |
| Ipamorelin acetate ≥98% | SML1322 | 50MG | $357 |
| IpamorelinAcetate | I739415 | 5mg | $50 |
| Ipamorelin Acetate | 452438 | 5mg | $305 |
| Ipamorelin | 5020AF | 5mg | $36 |
| More product size | |||
| Melting point | 144-147°C |
|---|---|
| Boiling point | 1185.5±65.0 °C(Predicted) |
| Density | 1.263±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Acetonitrile (Slightly, Heated), Methanol (Very Slightly), Water (Slightly) |
| pka | 13.04±0.46(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChIKey | NEHWBYHLYZGBNO-BVEPWEIPSA-N |
| SMILES | C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@H](CC1N=CNC=1)NC(=O)[C@](C)(C)N |
| FDA UNII | Y9M3S784Z6 |
Ipamorelin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1322 | Ipamorelin acetate ≥98% | 170851-70-4 | 10MG | $92.5 | 2025-07-31 | Buy |
| Sigma-Aldrich | SML1322 | Ipamorelin acetate ≥98% | 170851-70-4 | 50MG | $357 | 2025-07-31 | Buy |
| TRC | I739415 | IpamorelinAcetate | 170851-70-4 | 5mg | $50 | 2021-12-16 | Buy |
| Usbiological | 452438 | Ipamorelin Acetate | 170851-70-4 | 5mg | $305 | 2021-12-16 | Buy |
| AK Scientific | 5020AF | Ipamorelin | 170851-70-4 | 5mg | $36 | 2021-12-16 | Buy |
Ipamorelin Chemical Properties,Uses,Production
Description
Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.
Uses
Ipamorelin is a metabolite of growth hormone releasing peptides (GHRPs). Ipamorelin is a pentapeptide with strong growth hormone releasing potency that evokes insulin release from pancrease of normal and diabetic rats.
Uses
Ipamorelin was originally developed by Novo Nordisk, and was investigated in phase II clinical trials by Helsinn Therapeutics for the treatment of postoperative ileus, but was discontinued due to lack of efficacy.Ipamorelin has been used by athletes as a performance enhancing drug.
benefits
Ipamorelin has a wide range of benefits for the human body such as: reduced body fat, increased collagen production, increased lean muscle mass, improved sleep, increased cell repair and regeneration, elevated IGF-1, increased bone mineral content, counteracted glucocorticoid catabolism, decreased appetite stimulation compared to GHRP-6, decreased release of cortisol, prolactin and aldosterone. Decreased release of cortisol, prolactin and aldosterone.
Biochem/physiol Actions
Ipamorelin is a highly selective, potent pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and gastrin mimetic with growth hormone (GH) releasing activity. It mimics gastrin and binds to the gastrin receptor (or growth hormone secretion receptor, GHSR) in the brain, which selectively stimulates the pituitary gland to release growth hormone. This leads to elevated plasma GH levels, which affects many biological processes. In addition to being found in the brain, GHSR is found in the gastrointestinal tract, heart, lungs, liver, kidneys, pancreas, adipose tissue and immune cells. Unlike other growth hormone releasing peptides, ipamorelin stimulates the release of growth hormone only in a manner very similar to that of growth hormone releasing hormone[1].
Side effects
Ipamorelin is generally considered safe and well tolerated, with common side effects including dizziness, headache, nausea, diarrhoea and flushing. Allergic or serious adverse reactions are rare.
Synthesis
Ipamorelin was prepared from a total of 4.53 g of the peptide resin Boc-Aib-His (Trt)-D-2Nal-DPhe-Lys (Boc)-NH-resin according to the Fmoc strategy on an Applied Biosystems 431A peptide synthesizer in two identical runs (to obtain sufficient material) in 1 mmol scale using the FastMoc UV protocols supplied by the manufacturer, that employ HBTU mediated couplings in NMP and UV monitoring of the deprotection of the Fmoc protection group.
Description
Ipamorelin Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids, having a molecular mass of 711.85 Dalton and a Molecular formula of C38H49N9O5.
Background
Ipamorelin is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor and a growth hormone secretagogue. Ipamorelin is a pentapeptide that was derived from GHRP1. Ipamorelin significantly increases plasma growth hormone levels in both animals and humans. Like pralmorelin and GHRP-6, ipamorelin does not affect prolactin, FSH, LH or TSH levels. However, unlike GHRP2 and GHRP6, but as growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH.
References
[1] Ipamorelin[J]. Definitions, 2020. DOI:10.32388/22pzq4.
Ipamorelin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Deepharma | +86-18072861291 +1-7372336996 | eason@deefarma.com | China | 29 | 58 |
| Hebei Jiafan Trading Company Limited | +86-15354498258; +8615354498258 | sales01@jiafan88.com | China | 208 | 58 |
| Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 302 | 58 |
| Sea Biological Co.,LTD | +8613865152372 | tim@sea-biol.com | China | 71 | 58 |
| Hubei KDG Web Science&Technology Co., Ltd | +8618672314556 | sales@kdg-tech.com | China | 933 | 58 |
| TsurgeX Pharmaceutical Technology Co., Ltd. | +8613393959797 | master@tsurgex.com | China | 44 | 58 |
| Hebei Dangtong Import and export Co LTD | +86-86-4001020630 +8619831957301 | admin@hbdangtong.com | China | 1000 | 58 |
| Shandong Huizhihan Supply Chain Co., Ltd | +86-13363081709 +86-13363000288 | 3957328362@qq.com | China | 117 | 58 |
| DEI MEI YI YAO KE JI LLC | +852-52854821 +852-52854821 | cici71684@gmail.com | China | 879 | 58 |
| Rongchuang International | +8613175533356 | mihui41770@gmail.com | China | 245 | 58 |
Related articles
- Ipamorelin: Synthesis and its application research
- Ipamorelin is a new and potent synthetic pentapeptide which has distinct and specific growth hormone (GH)-releasing properties....
- Apr 21，2025
- The introduction of Ipamorelin
- Ipamorelin is a new and potent synthetic pentapeptide with distinct and specific growth hormone (GH)--releasing properties.
- Jun 17，2024
Related Qustion
Ask a questionView Lastest Price from Ipamorelin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-14 | 170851-70-4 | US $1.00 / g/ml | 1kit | 99.9% | 100KG | .GZ HONESTCHEM CO.,LTD | |
 |
2026-03-14 | Ipamorelin
170851-70-4
|
US $1.00 / kit | 1kit | 99.9% | 200 | .GZ HONESTCHEM CO.,LTD | |
 |
2026-03-14 | Ipamorelin
170851-70-4
|
US $80.00 / BOX | 1BOX | 99.9 | 9999 | Rongchuang International |
-
- 170851-70-4
- US $1.00 / g/ml
- 99.9%
- .GZ HONESTCHEM CO.,LTD
-
- Ipamorelin
170851-70-4
- US $1.00 / kit
- 99.9%
- .GZ HONESTCHEM CO.,LTD
-
- Ipamorelin
170851-70-4
- US $80.00 / BOX
- 99.9
- Rongchuang International
