(S)-3-Dimethylamino-3-phenylpropanol
- CAS No.
- 82769-75-3
- Chemical Name:
- (S)-3-Dimethylamino-3-phenylpropanol
- Synonyms
- Dapoxetine Impurity05;Dapoxetine Impurity 49;(S)-3-Dimethylamino-3-phenylpropanol;Benzenepropanol, g-(diMethylaMino)-, (gS)-;(3S)-3-(DiMethylaMino)-3-phenyl-1-propanol;(S)-3-(diMethyl aMino)-3-phenylpropan-1-ol;Benzenepropanol, γ-(dimethylamino)-, (γS)-;(+)-(S)-3-[N,N-Dimethylamino)-3-phenylpropanol;(S)-(+)-3-N,N-dimethylamino-3-phenylpropan-1-ol
- CBNumber:
- CB41120891
- Molecular Formula:
- C11H17NO
- Molecular Weight:
- 179.26
- MDL Number:
- MFCD09955476
- MOL File:
- 82769-75-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (S)-3-Dimethylamino-3-phenylpropanol | FD142888 | 100mg | $60 |
| (S)-3-(Dimethylamino)-3-phenylpropan-1-ol | W8638 | 250mg | $101 |
| (S)-3-Dimethylamino-3-phenylpropanol | FD142888 | 250mg | $120 |
| (S)-3-Dimethylamino-3-phenylpropanol | FD142888 | 500mg | $210 |
| (S)-3-Dimethylamino-3-phenylpropanol | FD142888 | 1g | $363 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 29062990 |
(S)-3-Dimethylamino-3-phenylpropanol price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FD142888 | (S)-3-Dimethylamino-3-phenylpropanol | 82769-75-3 | 100mg | $60 | 2021-12-16 | Buy |
| AK Scientific | W8638 | (S)-3-(Dimethylamino)-3-phenylpropan-1-ol | 82769-75-3 | 250mg | $101 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD142888 | (S)-3-Dimethylamino-3-phenylpropanol | 82769-75-3 | 250mg | $120 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD142888 | (S)-3-Dimethylamino-3-phenylpropanol | 82769-75-3 | 500mg | $210 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD142888 | (S)-3-Dimethylamino-3-phenylpropanol | 82769-75-3 | 1g | $363 | 2021-12-16 | Buy |
(S)-3-Dimethylamino-3-phenylpropanol Chemical Properties,Uses,Production
Chemical Properties
Colorless liquid
Uses
(+)-(S)-3-[N,N-Dimethylamino)-3-phenylpropanol used in the preparation of 5-hydroxytryptamine reuptake inhibitors.
Synthesis
50-00-0
82769-76-4
82769-75-3
General procedure for the synthesis of (S)-3-dimethylamino-3-phenylpropanol from formaldehyde and (S)-3-amino-3-phenylpropanol: (S)-3-Amino-3-phenylpropanol (1.5 kg) prepared as above was dissolved in 1.6 kg (88%, 30 mol) of formic acid, followed by addition of 2.8 kg (37%, 35 mol) of formaldehyde solution. The reaction mixture was heated to reflux for 8 hours. Upon completion of the reaction, a burst treatment was performed followed by concentration of the reaction solution under reduced pressure. To the concentrated solution, 2 L of 7K solution was added and the pH was adjusted with 10% aqueous sodium hydroxide solution to 12. Extraction was carried out with ethyl acetate (3 L × 4) and the organic phases were combined. The organic phase was washed twice with 6 L of saturated saline, respectively. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 1.65 kg of (S)-3-dimethylamino-3-phenylpropanol, which was analyzed by high-performance liquid chromatography (HPLC) with a purity of 97.36% and a yield of 93.02%. Ethyl acetate can be recovered for recycling.
References
[1] Patent: CN106883133, 2017, A. Location in patent: Paragraph 0048-0049; 0095; 0097
[2] Tetrahedron Asymmetry, 2007, vol. 18, # 17, p. 2099 - 2103
[3] Tetrahedron Asymmetry, 2006, vol. 17, # 5, p. 860 - 866
[4] European Journal of Organic Chemistry, 2014, vol. 2014, # 12, p. 2543 - 2548
[5] Tetrahedron, 2009, vol. 65, # 12, p. 2605 - 2609
(S)-3-Dimethylamino-3-phenylpropanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| Shanghai Yudiao Chemistry Technology Co.,Ltd | 02137285211 18964703211 | info@yudiaochem.com | CHINA | 238 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from (S)-3-Dimethylamino-3-phenylpropanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | (S)-3-Dimethylamino-3-phenylpropanol
82769-75-3
|
US $2.00 / KG | 1KG | 98% | 100g , 1kg, 5kg , 50kg | Career Henan Chemical Co |
-
- (S)-3-Dimethylamino-3-phenylpropanol
82769-75-3
- US $2.00 / KG
- 98%
- Career Henan Chemical Co
