ChemicalBook >> CAS DataBase List >>4Hydroxy Tamoxifen
4Hydroxy Tamoxifen
- CAS No.
- 82413-23-8
- Chemical Name:
- 4Hydroxy Tamoxifen
- Synonyms
- 4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
- CBNumber:
- CB41175806
- Molecular Formula:
- C26H29NO2
- Molecular Weight:
- 387.51
- MDL Number:
- MOL File:
- 82413-23-8.mol
Last updated:2023-05-18 11:31:21
| Melting point | 150-153°C |
|---|---|
| Boiling point | 514.4±50.0 °C(Predicted) |
| Density | 1.092±0.06 g/cm3(Predicted) |
| storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), Dichloromethane, Methanol (Slightly) |
| form | Solid |
| pka | 10.32±0.15(Predicted) |
| color | White to Off-White |
| Stability | Light Sensitive |
4Hydroxy Tamoxifen price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19519 | 4’-hydroxy Tamoxifen ≥98% (may contain up to 10% of the (E) isomer) | 82413-23-8 | 1mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 19519 | 4’-hydroxy Tamoxifen ≥98% (may contain up to 10% of the (E) isomer) | 82413-23-8 | 5mg | $513 | 2024-03-01 | Buy |
| TRC | H954730 | 4’-HydroxyTamoxifen(containsupto10%Eisomer) | 82413-23-8 | 25mg | $1695 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0001871 | 4'-HYDROXY TAMOXIFEN 95.00% | 82413-23-8 | 25MG | $2194.5 | 2021-12-16 | Buy |
| ApexBio Technology | C4624 | 4’-hydroxyTamoxifen | 82413-23-8 | 1mg | $187 | 2021-12-16 | Buy |
4Hydroxy Tamoxifen Chemical Properties,Uses,Production
Description
4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.
Chemical Properties
White Solid
Uses
A metabolite of Tamoxifen (T006000).
4Hydroxy Tamoxifen Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 24)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shenzhen Excellent Biomedical Technology Co.,Ltd. | +86-0755-26050679 +86-15915472436 | sale@ex-biotech.cn | China | 1031 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2210 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
82413-23-8(4Hydroxy Tamoxifen)Related Search:
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
Tamoxifen Impurity 3
4-Benzyloxy β-Hydroxy TaMoxifen
TaMoxifen DiMer
1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone
N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide
(E/Z Mixture)
Tamoxifen EP Impurity D
(E)-4-Alloxycarboxyl Tamoxifen
Endoxifen
desdimethyltamoxifen
1of4
4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol
4'-Hydroxy TaMoxifen (contains up to 10% E isoMer)
Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-
Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen)
82413-23-8
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals