ChemicalBook >> CAS DataBase List >>Melagatran
Melagatran
- CAS No.
- 159776-70-2
- Chemical Name:
- Melagatran
- Synonyms
- H-319/68;Melagatran;2-(((R)-2-((S)-2-((4-Carbamimidoylbenzyl)carbamoyl)azetidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)acetic acid;2-[[(1R)-2-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]azetidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]acetic acid;N-[(1R)-2-[(2S)-2-[[[[4-(Aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]glycine;Glycine, N-[(1R)-2-[(2S)-2-[[[[4-(aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]-
- CBNumber:
- CB41176409
- Molecular Formula:
- C22H31N5O4
- Molecular Weight:
- 429.51
- MDL Number:
- MFCD00945676
- MOL File:
- 159776-70-2.mol
Last updated:2023-09-04 15:51:00
| Melting point | 198-200°C |
|---|---|
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.12±0.10(Predicted) |
| color | White to Off-White |
| Stability | Hygroscopic |
| FDA UNII | 2A9QP32MD4 |
| ATC code | B01AE04 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H319-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Melagatran price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M208450 | Melagatran | 159776-70-2 | 5mg | $970 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 11499 | Melagatran 97% | 159776-70-2 | 5mg | $990 | 2021-12-16 | Buy |
| ChemScene | CS-0103405 | Melagatran | 159776-70-2 | 5mg | $1550 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611962 | Melagatran >98% | 159776-70-2 | 100mg | $1654.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000640 | MELAGATRAN 95.00% | 159776-70-2 | 10MG | $2194.5 | 2021-12-16 | Buy |
Melagatran Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic.
Definition
ChEBI: Melagatran is a member of the class of azetidines that is (2S)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2R)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group. It has a role as an anticoagulant, an EC 3.4.21.5 (thrombin) inhibitor and a serine protease inhibitor. It is a carboxamidine, a dicarboxylic acid monoamide, a non-proteinogenic alpha-amino acid, a secondary amino compound and a member of azetidines.
Melagatran Preparation Products And Raw materials
Raw materials
Preparation Products
Melagatran Suppliers
Global( 36)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
159776-70-2(Melagatran)Related Search:
H-319/68
Melagatran
N-[(1R)-2-[(2S)-2-[[[[4-(Aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]glycine
2-(((R)-2-((S)-2-((4-Carbamimidoylbenzyl)carbamoyl)azetidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)acetic acid
2-[[(1R)-2-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]azetidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]acetic acid
Glycine, N-[(1R)-2-[(2S)-2-[[[[4-(aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]-
159776-70-2
C22H31N5O4
Aromatics
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals
Aromatics Compounds