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N-[4-(-Carboxycyclohexylmethyl)]maleimide

N-[4-(-Carboxycyclohexylmethyl)]maleimide structure

CAS No.: 64987-82-2

Chemical Name:: N-[4-(-Carboxycyclohexylmethyl)]maleimide

Synonyms: Mal-Cyclohexanecarboxylicacid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl);4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid;4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95%;4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid;4-(Maleimidomethyl)cyclohexanecarboxylic Acid (Discontinued, see C177860);4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid;Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-;4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid

CBNumber:: CB41176520

Molecular Formula:: C12H15NO4

Molecular Weight:: 237.25

MDL Number:: MFCD03093740

MOL File:: 64987-82-2.mol

MSDS File:: SDS

Last updated:2024-03-27 15:49:59

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N-[4-(-Carboxycyclohexylmethyl)]maleimide Properties

Melting point	157-158°C
Boiling point	433.6±18.0 °C(Predicted)
Density	1.329±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform, Methanol
form	Solid
pka	4.80±0.10(Predicted)
color	Pale Yellow
InChI	InChI=1S/C12H15NO4/c14-10-5-6-11(15)13(10)7-8-1-3-9(4-2-8)12(16)17/h5-6,8-9H,1-4,7H2,(H,16,17)
InChIKey	LQILVUYCDHSGEU-UHFFFAOYSA-N
SMILES	C1(C(O)=O)CCC(CN2C(=O)C=CC2=O)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

HS Code

2925.19.9100

NFPA 704

	0
2		0

N-[4-(-Carboxycyclohexylmethyl)]maleimide price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M3218	4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid	64987-82-2	1G	$234	2024-03-01	Buy
TCI Chemical	M3218	4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid	64987-82-2	5G	$819	2024-03-01	Buy
TRC	C177860	N-[4-(-Carboxycyclohexylmethyl)]maleimide	64987-82-2	25mg	$110	2021-12-16	Buy
Biosynth Carbosynth	FC19767	N-[4-(-Carboxycyclohexylmethyl)]maleimide	64987-82-2	5G	$150	2021-12-16	Buy
AK Scientific	J95578	N-[4-(-Carboxycyclohexylmethyl)]maleimide	64987-82-2	250mg	$160	2021-12-16	Buy

Product number	Packaging	Price	Buy
M3218	1G	$234	Buy
M3218	5G	$819	Buy
C177860	25mg	$110	Buy
FC19767	5G	$150	Buy
J95578	250mg	$160	Buy

N-[4-(-Carboxycyclohexylmethyl)]maleimide Chemical Properties,Uses,Production

Description

4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical Properties

White Solid

Uses

An amino reactive reagent.

Uses

A sulfhydryl crosslinking reagent.

Definition

N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.

N-[4-(-Carboxycyclohexylmethyl)]maleimide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[4-(-Carboxycyclohexylmethyl)]maleimide Suppliers

Global( 80)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hongxiong	+undefined18915499068	Suzhouhongxiong@163.com	China	120	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Chengdu Pukang Biotechnology Co., Ltd	028-82550498	export@pu-kang.com	CHINA	210	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Henan Alfa Chemical Co., Ltd	+8618339805032	alfa4@alfachem.cn	China	12755	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
Chemtour Biotech Co., Ltd	+8617327281506	market@chemtour.com	China	1472	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068 +86-15680926068	1924344760@confluore.cn	China	2893	58

Supplier	Advantage
Hongxiong	58
Capot Chemical Co.,Ltd.	60
Chengdu Pukang Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58
Henan Alfa Chemical Co., Ltd	58
Nextpeptide Inc	58
Labnetwork lnc.	58
Chemtour Biotech Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Xian confluore Biological Technology Co., Ltd.	58

View Lastest Price from N-[4-(-Carboxycyclohexylmethyl)]maleimide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-03-27	Mal-Cyclohexanecarboxylicacid 64987-82-2	US $0.00 / g	25g	>95.00%	25g	Xian confluore Biological Technology Co., Ltd.

Mal-Cyclohexanecarboxylicacid
64987-82-2
US $0.00 / g
>95.00%
Xian confluore Biological Technology Co., Ltd.

64987-82-2(N-[4-(-Carboxycyclohexylmethyl)]maleimide)Related Search:

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Maleimide-PEG4-NHS Ester Maleimide-PEG2-NHS Ester 3-Maleimidopropionic acid Mal-PEG2-acid Mal-Amido-PEG4-acid

2-MALEIMIDOETHYLAMINE HCL 4-MALEIMIDOBUTYRIC ACID 1h-pyrrole-2,5-dione, 1-[2-(2-aminoethoxy)ethyl]-, 2,2,2-trifluoroacetate (1:1) Maleimide-SS-amine Deruxtecan

SMCC crosslinker SULFO-SMCC N-[4-(-Carboxycyclohexylmethyl)]maleimide

1of4

4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95% 4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid 4-(Maleimidomethyl)cyclohexanecarboxylic Acid (Discontinued, see C177860) 4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid 4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid 4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl) 4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]- Mal-Cyclohexanecarboxylicacid 64987-82-2 Cross Linking Reagents Maleimide Derivatives MTS & Sulfhydryl Active Reagents satralizumab-linker