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5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-

CAS No.
56990-57-9
Chemical Name:
5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-
Synonyms
NSC 87877;NSC 87877(free acid);XGMFVZOKHBRUTL-QURGRASLSA-N;8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonicacid;5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)-;5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-;(7e)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic Acid
CBNumber:
CB41243817
Molecular Formula:
C19H13N3O7S2
Molecular Weight:
459.45
MDL Number:
MFCD09971104
MOL File:
56990-57-9.mol
Last updated:2023-06-30 15:45:59

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Properties

storage temp. Store at +4°C
solubility ≥45.9 mg/mL in DMSO; insoluble in EtOH; ≥16.6 mg/mL in H2O with ultrasonic
form Powder

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H335-H315-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
NFPA 704
0
2 0

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14908 NSC 87877 ≥98% 56990-57-9 10mg $38 2024-03-01 Buy
Cayman Chemical 14908 NSC 87877 ≥98% 56990-57-9 25mg $79 2024-03-01 Buy
Cayman Chemical 14908 NSC 87877 ≥98% 56990-57-9 50mg $130 2024-03-01 Buy
Cayman Chemical 14908 NSC 87877 ≥98% 56990-57-9 100mg $220 2024-03-01 Buy
Tocris 2613 NSC87877 ≥98%(HPLC) 56990-57-9 50 $162 2021-12-16 Buy
Product number Packaging Price Buy
14908 10mg $38 Buy
14908 25mg $79 Buy
14908 50mg $130 Buy
14908 100mg $220 Buy
2613 50 $162 Buy

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Chemical Properties,Uses,Production

Uses

NSC 87877 is an inhibitor of SHP2 and SHP1 protein tyrosine phosphatases

Definition

ChEBI: 8-oxo-7-[(6-sulfo-2-naphthalenyl)hydrazinylidene]-5-quinolinesulfonic acid is a naphthalenesulfonic acid.

Biological Activity

Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC 50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μ M for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.

storage

Store at +4°C

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Preparation Products And Raw materials

Raw materials

Preparation Products

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Suppliers

Global( 85)Suppliers
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TargetMol Chemicals Inc.
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Career Henan Chemica Co
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InvivoChem
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LEAP CHEM CO., LTD.
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Nantong HI-FUTURE Biology Co., Ltd.
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PT CHEM GROUP LIMITED
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GIHI CHEMICALS CO.,LIMITED
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Wuhan Topule Biopharmaceutical Co., Ltd
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Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- Spectrum

5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- 8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonicacid NSC 87877 XGMFVZOKHBRUTL-QURGRASLSA-N 5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]- NSC 87877(free acid) (7e)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic Acid 56990-57-9 Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP).