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Rimonabant

Description References
Rimonabant
Rimonabant
CAS No.
168273-06-1
Chemical Name:
Rimonabant
Synonyms
A 281;ACOMPLIA;Sr 141716;RIMONABANT;Unii-rml78en3xe;Rimonabant base;Rimonabant base ,99%;RiMonabant (SR141716);RIMONABANT(ACOMPLIA,SR141716);N-piperidino-5-(4-chlorophenyl)-1(2,4-dichlorophenyl)-4-Methyl-pyrazole-3-carboxaMide
CBNumber:
CB4129374
Molecular Formula:
C22H21Cl3N4O
Formula Weight:
463.79
MOL File:
168273-06-1.mol

Rimonabant Properties

CAS DataBase Reference
168273-06-1(CAS DataBase Reference)

SAFETY

Rimonabant price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9000484 Rimonabant ≥98% 168273-06-1 5mg $42 2018-11-19 Buy
Cayman Chemical 9000484 Rimonabant ≥98% 168273-06-1 10mg $76 2018-11-19 Buy
Cayman Chemical 9000484 Rimonabant ≥98% 168273-06-1 25mg $168 2018-11-19 Buy
Cayman Chemical 9000484 Rimonabant ≥98% 168273-06-1 50mg $252 2018-11-19 Buy

Rimonabant Chemical Properties,Uses,Production

Description

Rimonabant is an inverse antagonist for the cannabinoid receptor (CB1). It acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid metabolism, including adipose tissue, the liver, gastrointestinal tract, and muscle. Thus, rimonabant constitutes a therapeutic approach to obesity and cardiovascular risk factors. As an anorectic antiobesity drug, it was used as an adjunct to diet and exercise for obese or overweight patients with associated risk factors in Europe in 2006. Nevertheless, adverse effects including suicidality, depression, and anxiety were reported, based on which rimonadant was withdrawn worldwide in 2008.
Andogenous cannabinoids are related to the pleasurable effect of nicotine, rimonabant, as a cannabinoid receptor blocker, is also being tested as a potential anti-smoking treatment.

References

[1] https://www.drugs.com/acomplia.html
[2] Leite CE, Mocelin CA, Petersen GO, Leal MB, Thiesen FV (2009) Rimonabant: an antagonist drug of the endocannabinoid system for the treatment of obesity, Pharmacol Rep., 61, 217-224

Uses

Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane

brand name

Acomplia (Sanofi-Synthe-labo).

Rimonabant Preparation Products And Raw materials

Raw materials

Preparation Products


Rimonabant Suppliers

Global( 157)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3218 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22060 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20795 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 14297 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20001 58
Shanghai YuMei Pharmaceutical Chemical Co., Ltd. 13671802554
-QQ627235036 xyfn@163.com China 547 58
Shenzhen Barker Chemical Technology Co., Ltd. 18825257575
0755-35352037 3535203737@qq.com China 309 58
Arden pharmaceutical &chemical Co., Ltd +86-(0)533-3595900 13793319233
+86-(0)533-3595900 info@chems.com.cn China 670 61
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0)21-58180499 sales@biochembest.com; market@biochembest.com China 6058 61

View Lastest Price from Rimonabant manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-16 Rimonabant
168273-06-1
US $8.00 / kg 1kg 98% 10MT career henan chemical co

168273-06-1(Rimonabant)Related Search:


  • 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-
  • 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
  • A 281
  • Sr 141716
  • Unii-rml78en3xe
  • Rimonabant base ,99%
  • N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-Methyl-1H-pyrazole-3-carboxyaMide
  • RiMonabant (SR141716)
  • N-piperidino-5-(4-chlorophenyl)-1(2,4-dichlorophenyl)-4-Methyl-pyrazole-3-carboxaMide
  • N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride Rimonabant(SR141716A) 158681-13-1 (HCl CAS)
  • Rimonabant base
  • 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamid
  • ACOMPLIA
  • RIMONABANT
  • RIMONABANT(ACOMPLIA,SR141716)
  • 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide
  • 168273-06-1
  • C22H21Cl3N4O
  • Weight Loss
  • SR141716
  • C22Cl3HN4O
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