Chinese Japanese Germany Korea

Isophorone diisocyanate

Isophorone diisocyanate
Isophorone diisocyanate structure
Chemical Name:
Isophorone diisocyanate
ipdi;Ncgc00091745-01;Isophorondiisocyanat;Isophorone diisocyan;IsophoroneDiisocyanat;ISOPHORONDIISOCYANATE;ISOPHORENEDIISOCYANATE;ISOPHORONE DIISOCYANATE;diisocyanated’isophorone;Isophorone diisocyanate,98%
Molecular Formula:
Formula Weight:
MOL File:

Isophorone diisocyanate Properties

Melting point:
Boiling point:
158-159 °C15 mm Hg(lit.)
1.049 g/mL at 25 °C(lit.)
vapor pressure 
0.0004 hPa (20 °C)
refractive index 
n20/D 1.484(lit.)
Flash point:
>230 °F
storage temp. 
Miscible with esters, ketones, ethers, and aromatic and aliphatic hydrocarbons.
Clear colorless to slightly yellow
explosive limit
Water Solubility 
<0.1 g/100 mL at 25 ºC
Moisture Sensitive
Exposure limits
TLV-TWA 0.0454 mg/m3 (0.005 ppm) (ACGIH and NIOSH); ceiling 0.181 mg/m3 (0.02 ppm)/10 min (NIOSH). .
Reacts with all substances containing active hydrogen, such as acids, amines, water, phenols, mercaptans, amides, urea. Probably moisture sensitive.
CAS DataBase Reference
4098-71-9(CAS DataBase Reference)
EPA Substance Registry System
Cyclohexane, 5-isocyanato-1-(isocyanatomethyl)- 1,3,3-trimethyl-(4098-71-9)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  T,N
Risk Statements  23-36/37/38-42/43-51/53-22
Safety Statements  26-28-38-45-61
RIDADR  UN 2290 6.1/PG 3
WGK Germany  2
RTECS  NQ9370000
Autoignition Temperature 430 °C
HazardClass  6.1
PackingGroup  III
HS Code  29291090
Hazardous Substances Data 4098-71-9(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 4825 mg/kg LD50 dermal Rat > 7000 mg/kg
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P320 Specific treatment is urgent (see … on this label).
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

NFPA 704

Diamond Hazard Value Description
2 1
Health   2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
Flammability   1 Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
Instability   1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)

(NFPA, 2010)

Isophorone diisocyanate price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 317624 Isophorone diisocyanate 98% 4098-71-9 5ml $26.3 2018-11-13 Buy
Sigma-Aldrich 317624 Isophorone diisocyanate 98% 4098-71-9 1l $185 2018-11-13 Buy
TCI Chemical I0314 Isophorone Diisocyanate (mixture of isomers) >99.0%(GC) 4098-71-9 25mL $21 2018-11-22 Buy
TCI Chemical I0314 Isophorone Diisocyanate (mixture of isomers) >99.0%(GC) 4098-71-9 500mL $88 2018-11-22 Buy
Alfa Aesar L13759 Isophorone diisocyanate, mixture of isomers, 98% 4098-71-9 5g $19.9 2018-11-13 Buy

Isophorone diisocyanate Chemical Properties,Uses,Production

Chemical Properties

colourless or slightly yellow liquid


Yields polyurethanes with high stability, resistance to light discoloration, and chemical resistance.


Isophorone diisocyanate (IPDI) is used in theproduction of high-quality coatings, polyurethane paints, and varnishes and as an elastomer for casting compounds..


ChEBI: A diisocyanate in which the two isocyanate groups are linked by an isophorone substituent.

General Description

A clear to light-yellow liquid. Slightly denser than water and insoluble in water. Toxic by inhalation and skin absorption. Very irritating to skin. Used to make polyurethane coatings.

Air & Water Reactions

Insoluble in water. Isophorone diisocyanate may be sensitive to moisture.

Reactivity Profile

Isophorone diisocyanate reacts with all substances containing active hydrogen atoms such as water, alcohols, phenols, amines, mercaptans, amides, urethanes and ureas.


A severe irritant, toxic by skin absorption.

Health Hazard

Like most other isocyanates, IPDI exhibitsmoderate toxicity via inhalation. The acutetoxic symptoms are somewhat similar tothose of toluene-2,4- diisocyanate and diphenylmethane-4,4'-diisocyanate. Thus thetoxicity of such types is a characteristic ofthe -N=C=O functional group and to agreat extent is independent of the nature ofthe ring.
Inhalation of its vapor can cause bronchitis, asthma, tightness of chest, and dyspnea in humans. Recovery from these effectsmay occur in a short period from a lowconcentration exposure.
IPDI is an irritant to the skin and eyes.Exposure to this compound produces skinsensitization and eczema. Its oral toxicity isvery low.
LC50 value, inhalation (rats): 123 mg/m3/4 hrLD50 value, skin (rats): 1060 mg/m3
There is no report of its carcinogenic orreproductive effects in animals or humans.

Health Hazard

Isophorone diisocyanate is highly toxic by inhalation and moderately toxic through the skin. (Non-Specific -- Isocyanates) People with skin or respiratory problems should avoid exposure.

Fire Hazard

When heated to decomposition, Isophorone diisocyanate emits toxic fumes of nitrogen oxides.

Waste Disposal

Disposal is by chemical incineration of IPDIsolution in a combustible solvent.

Isophorone diisocyanate Preparation Products And Raw materials

Raw materials

Preparation Products

Isophorone diisocyanate Suppliers

Global( 150)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22064 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20743 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32606 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 CHINA 2546 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24093 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4696 58
Zhengzhou Ruke Biological Co., Ltd. 15981811963;15838371839
QQ:1410472904 China 5161 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30273 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 China 24637 81

Isophorone diisocyanate Spectrum

4098-71-9(Isophorone diisocyanate )Related Search:

Copyright 2017 © ChemicalBook. All rights reserved