ChemicalBook >> CAS DataBase List >>picromycin

picromycin

picromycin structure

CAS No.: 19721-56-3

Chemical Name:: picromycin

Synonyms: picromycin;Pikromycin;Amaromycin;Albomycetin;Antibiotic B 62169A;(3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3-(dimethylamino)-3,4,6-trideoxy-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradeca-11-ene-2,4,10-trione;Oxacyclotetradec-11-ene-2,4,10-trione, 14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3R,5R,6S,7S,9R,11E,13S,14R)-

CBNumber:: CB41308804

Molecular Formula:: C28H47NO8

Molecular Weight:: 525.68

MDL Number:

MOL File:: 19721-56-3.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

Request For Quotation

picromycin Properties

Melting point	169.5℃
alpha	D24 +8.2° (c = 3.5 in ethanol); D20 -33.5° (c = 2.07 in chloroform); D24 -50.2° (c = 6.3 in chloroform)
storage temp.	Store at -20°C
solubility	DMSO: soluble
form	A crystalline solid
Boiling point	688.1±55.0 °C(Predicted)
Density	1.14±0.1 g/cm3(Predicted)
pka	11.15±0.70(Predicted)
color	White crystalline
EWG's Food Scores	1
FDA UNII	FBM8G3Z439

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

NFPA 704

	0
2		0

picromycin price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	207341	Pikromycin	19721-56-3	1mg	$316	2021-12-16	Buy
TRC	P991783	Pikromycin	19721-56-3	5mg	$780	2021-12-16	Buy
Adipogen Life Sciences	BVT-0400-M005	Pikromycin ≥95%(HPLC)	19721-56-3	5mg	$240	2021-12-16	Buy
American Custom Chemicals Corporation	API0010176	PICROMYCIN 95.00%	19721-56-3	5MG	$519.46	2021-12-16	Buy

Product number	Packaging	Price	Buy
207341	1mg	$316	Buy
P991783	5mg	$780	Buy
BVT-0400-M005	5mg	$240	Buy
API0010176	5MG	$519.46	Buy

picromycin Chemical Properties,Uses,Production

Uses

Pikromycin is an inhibitor of Prolyl endopeptidase.

Definition

ChEBI: A macrolide antibiotic that is biosynthesised by Streptomyces venezuelae.

Enzyme inhibitor

This polyketide (FW = 525.68 g/mol; CAS 19721-56-3; bitter-tasting solid; low water solubility; soluble in benzene and acetone) from Actinomyces spp., and originally spelled pikromycin, was the first identified macrolide antibiotic. Picromycin is most likely produced as the inactive diglucoside and liberated extracellularly as the active antibiotic through the action of a b-glucosidase.

storage

+4°C

picromycin synthesis

Synthesis of picromycin from Oxacyclotetradec-11-ene-2,4,10-trione, 6-[[2-O-acetyl-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-, (3R,5R,6S,7S,9R,11E,13S,14R)-

picromycin Preparation Products And Raw materials

Raw materials

Oxacyclotetradec-11-ene-2,4,10-trione, 6-[[2-O-acetyl-3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-, (3R,5R,6S,7S,9R,11E,13S,14R)-

Preparation Products

picromycin Suppliers

Global( 25)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3989	66
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
BOC Sciences	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Aladdin Scientific	58
Shanghai Tauto Biotech Co., Ltd.	66
Shanghai EFE Biological Technology Co., Ltd.	58
Lynnchem	58
Novachemistry	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Energy Chemical	58

19721-56-3(picromycin)Related Search:

ACETOACETIC ACID SEC-BUTYL ESTER METHYL 2,4-DIMETHYL-3-OXOPENTANOATE Isobutyl acetoacetate Methyl isobutyrylacetate METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL

Ethyl isobutyrylacetate 3-BUTENE-1,2-DIOL Telithromycin intermediate (7A) METHYL 8-METHYLNONANOATE ETHYL 4-METHYLOCTANOATE

propyl 2-methylpentanoate 3-METHYL-1-PENTEN-3-OL FEMA 2200 ETHYL 10-UNDECENOATE ACETOACETIC ACID N-PROPYL ESTER

delta-Nonalactone 4-ISOBUTOXY-2-BUTANONE Ethyl butyrylacetate

1of4

picromycin (3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3-(dimethylamino)-3,4,6-trideoxy-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradeca-11-ene-2,4,10-trione Albomycetin Amaromycin Pikromycin Antibiotic B 62169A Oxacyclotetradec-11-ene-2,4,10-trione, 14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3R,5R,6S,7S,9R,11E,13S,14R)- 19721-56-3 C28H47NO8